UniProt P27577
Protein C-ets-1 (P27577)
Protein C-ets-1 (UniProt P27577): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P27577
- Protein
- Protein C-ets-1
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
18 records of P27577 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K78 | Pax5(1-149)+Ets-1(331-440)+DNA | x-ray diffraction | B, F | — | — |
| 1K78 | PAX5(1-149)+ETS-1(331-440)+DNA | x-ray diffraction | B, F | — | — |
| 1K79 | Ets-1(331-440)+GGAA duplex | x-ray diffraction | A, D | — | — |
| 1K79 | Ets-1(331-440)+GGAA duplex | x-ray diffraction | A, D | — | — |
| 1K7A | Ets-1(331-440)+GGAG duplex | x-ray diffraction | A, D | — | — |
| 1K7A | Ets-1(331-440)+GGAG duplex | x-ray diffraction | A, D | — | — |
| 1MD0 | CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1 | x-ray diffraction | A, B | — | — |
| 1MD0 | Crystal structure of an inhibited fragment of ets-1 | x-ray diffraction | A, B | — | — |
| 1MDM | Inhibited fragment of ets-1 and paired domain of PAX5 bound to DNA | x-ray diffraction | B | — | — |
| 1MDM | Inhibited fragment of ets-1 and paired domain of PAX5 bound to DNA | x-ray diffraction | B | — | — |
| 1R36 | NMR-based structure of autoinhibited murine Ets-1 deltaN301 | solution nmr | A | — | — |
| 1R36 | NMR-based structure of autoinhibited murine ets-1 DELTAN301 | solution nmr | A | — | — |
| 2KMD | Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to… | solution nmr | A | — | — |
| 2KMD | RAS signaling requires dynamic properties of ETS1 for phosphorylation- enhanced binding to… | solution nmr | A | — | — |
| 6DA1 | ETS1 in complex with synthetic srr mimic | x-ray diffraction | A, B | NH2, SO4 | — |
| 6DAT | ETS1 in complex with synthetic SRR mimic | x-ray diffraction | A, B, C, D | SO4 | 3 (best 0.77) |
| 6DAT | ETS1 in complex with synthetic srr mimic | x-ray diffraction | A, B, C, D | NH2, SO4 | — |
| P27577 | AlphaFold monomer V2.0 prediction for protein C-ets-1 (P27577) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1K78 chain B against the predicted model P27577: TM-score 0.99, RMSD 0.44 Å
- 1K78 chain B against the predicted model P27577: TM-score 0.99, RMSD 0.44 Å
- 1K79 chain A against the predicted model P27577: TM-score 0.98, RMSD 0.57 Å
- 1K79 chain A against the predicted model P27577: TM-score 0.98, RMSD 0.57 Å
- 1K7A chain A against the predicted model P27577: TM-score 0.98, RMSD 0.59 Å
- 1K7A chain A against the predicted model P27577: TM-score 0.98, RMSD 0.59 Å
- 1K79 chain D against the predicted model P27577: TM-score 0.97, RMSD 0.63 Å
- 1K79 chain D against the predicted model P27577: TM-score 0.97, RMSD 0.63 Å
- 1K78 chain F against the predicted model P27577: TM-score 0.97, RMSD 0.63 Å
- 1K78 chain F against the predicted model P27577: TM-score 0.97, RMSD 0.63 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.