UniProt P27348
14-3-3 protein theta (P27348)
14-3-3 protein theta (UniProt P27348): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P27348
- Protein
- 14-3-3 protein theta
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 33 · 4 records with a druggable one
Structures
13 records of P27348 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BTP | 14-3-3 Protein Theta (Human) Complexed to Peptide | x-ray diffraction | A, B | — | — |
| 2BTP | 14-3-3 protein theta (human) complexed to peptide | x-ray diffraction | A, B | — | — |
| 5IQP | 14-3-3 protein tau isoform | x-ray diffraction | A, B | SO4 | 3 (best 0.55) |
| 5IQP | 14-3-3 protein tau isoform | x-ray diffraction | A, B | — | — |
| 6BCR | Complex of 14-3-3 theta with an IRSP53 peptide phosphorylated at T340 | x-ray diffraction | A, B, E, F | MG | — |
| 6BD2 | Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366 | x-ray diffraction | A, B | — | 7 (best 0.62) |
| 6BD2 | Complex of 14-3-3 theta with an IRSP53 peptide doubly-phosphorylated at T340 and S366 | x-ray diffraction | A, B | — | — |
| 6BQT | Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360 | x-ray diffraction | A, B, D, E, G, H, J, K | — | 20 (best 0.77) |
| 6BQT | Complex of 14-3-3 theta with an IRSP53 peptide doubly-phosphorylated at T340 and T360 | x-ray diffraction | A, B, D, E, G, H, J, K | — | — |
| 6KZG | 14-3-3 protein in complex with cic S301 phosphorylated peptide | x-ray diffraction | A, B | — | — |
| 6KZH | 14-3-3 protein in Complex with CIC S173 phosphorylated peptide | x-ray diffraction | A, B | — | 3 (best 0.60) |
| 6KZH | 14-3-3 protein in complex with cic S173 phosphorylated peptide | x-ray diffraction | A, B | — | — |
| P27348 | AlphaFold monomer V2.0 prediction for 14-3-3 protein theta (P27348) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2BTP chain B against the predicted model P27348: TM-score 0.99, RMSD 0.60 Å
- 2BTP chain B against the predicted model P27348: TM-score 0.99, RMSD 0.60 Å
- 5IQP chain B against the predicted model P27348: TM-score 0.99, RMSD 0.64 Å
- 5IQP chain B against the predicted model P27348: TM-score 0.99, RMSD 0.64 Å
- 6BD2 chain B against the predicted model P27348: TM-score 0.99, RMSD 0.69 Å
- 6BD2 chain B against the predicted model P27348: TM-score 0.99, RMSD 0.69 Å
- 6BQT chain D against the predicted model P27348: TM-score 0.99, RMSD 0.81 Å
- 6BQT chain D against the predicted model P27348: TM-score 0.99, RMSD 0.81 Å
- 6BQT chain H against the predicted model P27348: TM-score 0.98, RMSD 0.80 Å
- 6BQT chain H against the predicted model P27348: TM-score 0.98, RMSD 0.80 Å
Elsewhere
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