UniProt P26992
Ciliary neurotrophic factor receptor subunit alpha (P26992)
Ciliary neurotrophic factor receptor subunit alpha (UniProt P26992): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P26992
- Protein
- Ciliary neurotrophic factor receptor subunit alpha
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 4 records with a druggable one
Structures
7 records of P26992 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1UC6 | Solution Structure of the Carboxyl Terminal Domain of the Ciliary Neurotrophic Factor Receptor | solution nmr | A | — | — |
| 1UC6 | Solution structure of the carboxyl terminal domain of the ciliary neurotrophic factor receptor | solution nmr | A | — | — |
| 8D74 | Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region | electron microscopy | C | NAG | 4 (best 0.68) |
| 8D7E | Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies | electron microscopy | C | NAG | 5 (best 0.77) |
| 8D7H | Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha | electron microscopy | C, G | NAG | 4 (best 0.56) |
| 8D7R | Cryo-EM structure of human CLCF1 signaling complex: model containing the interaction core region | electron microscopy | C | NAG | 2 (best 0.65) |
| P26992 | AlphaFold monomer V2.0 prediction for ciliary neurotrophic factor receptor subunit alpha (P26992) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 8D74 chain C against the predicted model P26992: TM-score 0.97, RMSD 0.92 Å
- 8D7R chain C against the predicted model P26992: TM-score 0.95, RMSD 1.23 Å
- 8D7E chain C against the predicted model P26992: TM-score 0.95, RMSD 1.48 Å
- 8D7H chain C against the predicted model P26992: TM-score 0.95, RMSD 1.49 Å
- 8D7H chain G against the predicted model P26992: TM-score 0.95, RMSD 1.50 Å
- 1UC6 chain A against the predicted model P26992: TM-score 0.88, RMSD 1.69 Å
- 1UC6 chain A against the predicted model P26992: TM-score 0.88, RMSD 1.69 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.