UniProt P26441
Ciliary neurotrophic factor (P26441)
Ciliary neurotrophic factor (UniProt P26441): 3 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P26441
- Protein
- Ciliary neurotrophic factor
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
4 records of P26441 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CNT | Ciliary neurotrophic factor | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 1CNT | Ciliary neurotrophic factor | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 8D74 | Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region | electron microscopy | D | — | 8 (best 0.68) |
| P26441 | AlphaFold monomer V2.0 prediction for ciliary neurotrophic factor (P26441) | predicted | A | — | — |
Experiment against prediction
- 1CNT chain 3 against the predicted model P26441: TM-score 0.97, RMSD 0.77 Å
- 1CNT chain 3 against the predicted model P26441: TM-score 0.97, RMSD 0.77 Å
- 1CNT chain 4 against the predicted model P26441: TM-score 0.97, RMSD 0.78 Å
- 1CNT chain 4 against the predicted model P26441: TM-score 0.97, RMSD 0.78 Å
- 8D74 chain D against the predicted model P26441: TM-score 0.95, RMSD 1.42 Å
- 1CNT chain 2 against the predicted model P26441: TM-score 0.94, RMSD 1.27 Å
- 1CNT chain 2 against the predicted model P26441: TM-score 0.94, RMSD 1.27 Å
- 1CNT chain 1 against the predicted model P26441: TM-score 0.94, RMSD 1.53 Å
- 1CNT chain 1 against the predicted model P26441: TM-score 0.94, RMSD 1.53 Å
Elsewhere
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