UniProt P26393
Glucose-1-phosphate thymidylyltransferase (P26393)
Glucose-1-phosphate thymidylyltransferase (UniProt P26393), EC 2.7.7.24: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 75 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P26393
- Protein
- Glucose-1-phosphate thymidylyltransferase
- EC
- 2.7.7.24
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 75 · 5 records with a druggable one
Structures
5 records of P26393 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3PKP | Q83S Variant of S. Enterica RmlA with dATP | x-ray diffraction | A, B, C, D, I, J, K, L | DTP, MG | 20 (best 0.76) |
| 3PKP | Q83S variant of S. enterica rmla with datp | x-ray diffraction | A, B, C, D, I, J, K, L | DTP, MG | 20 (best 0.76) |
| 3PKQ | Q83D Variant of S. Enterica RmlA with dGTP | x-ray diffraction | A, B, C, D | DGT, MG | 16 (best 0.75) |
| 3PKQ | Q83D variant of S. enterica rmla with dgtp | x-ray diffraction | A, B, C, D | DGT, MG | 16 (best 0.75) |
| P26393 | AlphaFold monomer V2.0 prediction for glucose-1-phosphate thymidylyltransferase (P26393) | predicted | A | — | 3 (best 0.69) |
Ligands
Experiment against prediction
- 3PKQ chain A against the predicted model P26393: TM-score 0.98, RMSD 0.82 Å
- 3PKQ chain A against the predicted model P26393: TM-score 0.98, RMSD 0.82 Å
- 3PKQ chain D against the predicted model P26393: TM-score 0.98, RMSD 1.01 Å
- 3PKQ chain D against the predicted model P26393: TM-score 0.98, RMSD 1.01 Å
- 3PKQ chain C against the predicted model P26393: TM-score 0.97, RMSD 1.18 Å
- 3PKQ chain C against the predicted model P26393: TM-score 0.97, RMSD 1.18 Å
- 3PKQ chain B against the predicted model P26393: TM-score 0.97, RMSD 1.27 Å
- 3PKQ chain B against the predicted model P26393: TM-score 0.97, RMSD 1.27 Å
- 3PKP chain C against the predicted model P26393: TM-score 0.96, RMSD 1.37 Å
- 3PKP chain C against the predicted model P26393: TM-score 0.96, RMSD 1.37 Å
Elsewhere
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