UniProt P26262
Plasma kallikrein (P26262)
Plasma kallikrein (UniProt P26262), EC 3.4.21.34: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P26262
- Protein
- Plasma kallikrein
- EC
- 3.4.21.34
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of P26262 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GVT | Crystal structures of the serine protease domain of murine plasma kallikrein | x-ray diffraction | A, B | BMA, MAN | — |
| 5GVT | Crystal structures of the serine protease domain of murine plasma kallikrein | x-ray diffraction | A, B | — | — |
| 6A8O | Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor… | x-ray diffraction | A, B | MAN, MRZ | 7 (best 0.67) |
| 6A8O | Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor… | x-ray diffraction | A, B | MAN, MRZ | — |
| P26262 | AlphaFold monomer V2.0 prediction for plasma kallikrein (P26262) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6A8O chain B against the predicted model P26262: TM-score 0.98, RMSD 0.60 Å
- 5GVT chain A against the predicted model P26262: TM-score 0.98, RMSD 0.79 Å
- 5GVT chain A against the predicted model P26262: TM-score 0.98, RMSD 0.79 Å
- 5GVT chain B against the predicted model P26262: TM-score 0.97, RMSD 0.80 Å
- 5GVT chain B against the predicted model P26262: TM-score 0.97, RMSD 0.80 Å
- 6A8O chain A against the predicted model P26262: TM-score 0.97, RMSD 0.84 Å
- 6A8O chain A against the predicted model P26262: TM-score 0.97, RMSD 0.84 Å
Elsewhere
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