UniProt P25963
NF-kappa-B inhibitor alpha (P25963)
NF-kappa-B inhibitor alpha (UniProt P25963): 6 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P25963
- Protein
- NF-kappa-B inhibitor alpha
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
7 records of P25963 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IKN | IKAPPABALPHA/NF-kappab complex | x-ray diffraction | D | — | — |
| 1IKN | IKAPPABALPHA/NF-kappab complex | x-ray diffraction | D | — | — |
| 1NFI | I-kappa-B-ALPHA/NF-kappa-B complex | x-ray diffraction | E, F | — | — |
| 1NFI | I-kappa-B-ALPHA/NF-kappa-B complex | x-ray diffraction | E, F | — | — |
| 6Y1J | 14-3-3 sigma in complex with IkappaBalpha pS63 peptide | x-ray diffraction | P | — | 1 (best 0.54) |
| 6Y1J | 14-3-3 sigma in complex with ikappabalpha PS63 peptide | x-ray diffraction | P | — | — |
| P25963 | AlphaFold monomer V2.0 prediction for nf-kappa-B inhibitor alpha (P25963) | predicted | A | — | — |
Experiment against prediction
- 1NFI chain E against the predicted model P25963: TM-score 0.99, RMSD 0.63 Å
- 1NFI chain E against the predicted model P25963: TM-score 0.99, RMSD 0.63 Å
- 1IKN chain D against the predicted model P25963: TM-score 0.92, RMSD 1.62 Å
- 1IKN chain D against the predicted model P25963: TM-score 0.92, RMSD 1.62 Å
- 6Y1J chain P against the predicted model P25963: TM-score 0.52, RMSD 1.57 Å
- 6Y1J chain P against the predicted model P25963: TM-score 0.52, RMSD 1.57 Å
Elsewhere
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