UniProt P25942
Tumor necrosis factor receptor superfamily member 5 (P25942)
Tumor necrosis factor receptor superfamily member 5 (UniProt P25942): 23 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P25942
- Protein
- Tumor necrosis factor receptor superfamily member 5
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 3 records with a druggable one
Structures
24 records of P25942 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CZZ | Structure of TNF receptor associated factor 2 in complex with a 17-residue CD40 peptide | x-ray diffraction | D, E | — | — |
| 1CZZ | Structure of TNF receptor associated factor 2 in complex with a 17- residue CD40 peptide | x-ray diffraction | D, E | — | — |
| 1D00 | Structure of TNF receptor associated factor 2 in complex with a 5-residue CD40 peptide | x-ray diffraction | I, J, K, L, M, N, O, P | — | — |
| 1D00 | Structure of TNF receptor associated factor 2 in complex with a 5- residue CD40 peptide | x-ray diffraction | I, J, K, L, M, N, O, P | — | — |
| 1FLL | Molecular basis for CD40 signaling mediated by TRAF3 | x-ray diffraction | X, Y | — | — |
| 1FLL | Molecular basis for CD40 signaling mediated by TRAF3 | x-ray diffraction | X, Y | — | — |
| 1LB6 | TRAF6-CD40 Complex | x-ray diffraction | B | — | — |
| 1LB6 | TRAF6-CD40 complex | x-ray diffraction | B | — | — |
| 3QD6 | Crystal structure of the CD40 and CD154 (CD40L) complex | x-ray diffraction | R, S, T, U | — | — |
| 3QD6 | Crystal structure of the CD40 and CD154 (CD40L) complex | x-ray diffraction | R, S, T, U | — | — |
| 5DMI | Structure of the extracellular domain of the CD40 in complex with CHI220 FAB | x-ray diffraction | A | — | — |
| 5DMI | Structure of the extracellular domain of the CD40 in complex with CHI220 Fab | x-ray diffraction | A | — | — |
| 5DMJ | Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB | x-ray diffraction | A, D, F | K | — |
| 5DMJ | Structure of the extracellular domain of the CD40 in complex with 3H56-5 dab | x-ray diffraction | A, D, F | — | — |
| 5IHL | Structure of the extracellular domain of the CD40 in complex with 3H56-5 dab | x-ray diffraction | A, D, F, H | SO4 | — |
| 5IHL | Structure of the extracellular domain of the CD40 in complex with 3H56-5 dab | x-ray diffraction | A, D, F, H | — | — |
| 6FAX | Complex of human CD40 ectodomain with lob 7.4 Fab | x-ray diffraction | R | — | — |
| 6PE8 | Crystal structure of CD40/ABBV-323 FAB complex | x-ray diffraction | T, U | SO4 | 4 (best 0.63) |
| 6PE8 | Crystal structure of CD40/ABBV-323 Fab complex | x-ray diffraction | T, U | SO4 | — |
| 6PE9 | Crystal Structure of CD40 complexed to FAB516 | x-ray diffraction | G, I, J, U, V | SO4 | 9 (best 0.78) |
| 6PE9 | Crystal structure of CD40 complexed to FAB516 | x-ray diffraction | G, I, J, U, V | SO4 | — |
| 7P3I | Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 darpin protein | x-ray diffraction | A, C | NA | — |
| 8YX1 | CD40 in complex with Bleselumab Fab | x-ray diffraction | R, C | — | 7 (best 0.66) |
| P25942 | AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 5 (P25942) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6PE9 chain J against the predicted model P25942: TM-score 0.93, RMSD 1.07 Å
- 6PE9 chain J against the predicted model P25942: TM-score 0.93, RMSD 1.07 Å
- 6PE9 chain I against the predicted model P25942: TM-score 0.93, RMSD 1.21 Å
- 6PE9 chain I against the predicted model P25942: TM-score 0.93, RMSD 1.21 Å
- 6PE9 chain V against the predicted model P25942: TM-score 0.93, RMSD 0.91 Å
- 6PE9 chain V against the predicted model P25942: TM-score 0.93, RMSD 0.91 Å
- 5DMI chain A against the predicted model P25942: TM-score 0.91, RMSD 1.45 Å
- 5DMI chain A against the predicted model P25942: TM-score 0.91, RMSD 1.45 Å
- 6FAX chain R against the predicted model P25942: TM-score 0.90, RMSD 1.45 Å
- 1D00 chain I against the predicted model P25942: TM-score 0.90, RMSD 0.17 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.