UniProt P25705
ATP synthase subunit alpha, mitochondrial (P25705)
ATP synthase subunit alpha, mitochondrial (UniProt P25705): 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P25705
- Protein
- ATP synthase subunit alpha, mitochondrial
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 80 · 5 records with a druggable one
Structures
6 records of P25705 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8H9L | Human ATP synthase F1 domain, state 3a | electron microscopy | A, B, C | ATP, MG, ADP | 20 (best 0.87) |
| 8H9S | Human ATP synthase state 1 (combined) | electron microscopy | A, B, C | ATP, MG, ADP | 14 (best 0.89) |
| 8H9T | Human ATP synthase state 2 (combined) | electron microscopy | C, A, B | ATP, MG, ADP | 15 (best 0.87) |
| 8H9U | Human ATP synthase state 3a (combined) | electron microscopy | A, B, C | ATP, MG, ADP | 16 (best 0.86) |
| 8KI3 | Structure of the human ATP synthase bound to bedaquiline (composite) | electron microscopy | A, B, C | ATP, MG, ADP | 15 (best 0.87) |
| P25705 | AlphaFold monomer V2.0 prediction for ATP synthase subunit alpha, mitochondrial (P25705) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8H9T chain A against the predicted model P25705: TM-score 0.99, RMSD 0.61 Å
- 8H9U chain C against the predicted model P25705: TM-score 0.99, RMSD 0.76 Å
- 8H9L chain C against the predicted model P25705: TM-score 0.99, RMSD 0.76 Å
- 8H9T chain C against the predicted model P25705: TM-score 0.99, RMSD 0.93 Å
- 8H9S chain A against the predicted model P25705: TM-score 0.99, RMSD 1.04 Å
- 8H9L chain A against the predicted model P25705: TM-score 0.99, RMSD 1.18 Å
- 8H9U chain A against the predicted model P25705: TM-score 0.99, RMSD 1.19 Å
- 8KI3 chain A against the predicted model P25705: TM-score 0.99, RMSD 1.06 Å
- 8H9L chain B against the predicted model P25705: TM-score 0.98, RMSD 1.00 Å
- 8H9U chain B against the predicted model P25705: TM-score 0.98, RMSD 1.00 Å
Elsewhere
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