UniProt P25559
Sister chromatid cohesion protein DCC1 (P25559)
Sister chromatid cohesion protein DCC1 (UniProt P25559): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 74 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P25559
- Protein
- Sister chromatid cohesion protein DCC1
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 74 · 7 records with a druggable one
Structures
15 records of P25559 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MSM | Structure of the DCC1-CTF8-CTF18C trimer | x-ray diffraction | A, D | — | — |
| 5MSN | Structure of the Dcc1 Protein | x-ray diffraction | A, B, C, D | — | 18 (best 0.80) |
| 5MSN | Structure of the DCC1 protein | x-ray diffraction | A, B, C, D | — | — |
| 5OKC | Crystal structure of the Ctf18-1-8 module from Ctf18-RFC | x-ray diffraction | A, B | NO3 | 14 (best 0.56) |
| 5OKC | Crystal structure of the CTF18-1-8 module from CTF18-rfc | x-ray diffraction | A, B | NO3 | — |
| 5OKI | Crystal structure of the Ctf18-1-8 module from Ctf18-RFC in complex with a 63 kDa fragment of DNA… | x-ray diffraction | C, G | — | 13 (best 0.71) |
| 5OKI | Crystal structure of the CTF18-1-8 module from CTF18-rfc in complex with a 63 kda fragment of DNA… | x-ray diffraction | C, G | — | — |
| 6S1C | P3221 crystal form of the CTF18-1-8/POL2(1-528) complex | x-ray diffraction | B, F | — | — |
| 6S2E | Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon | electron microscopy | B | — | 9 (best 0.77) |
| 6S2E | Cryo-EM structure of CTF18-1-8 in complex with the catalytic domain of DNA polymerase epsilon | electron microscopy | B | — | — |
| 6S2F | Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon… | electron microscopy | B | — | 11 (best 0.83) |
| 6S2F | Cryo-EM structure of CTF18-1-8 in complex with the catalytic domain of DNA polymerase epsilon… | electron microscopy | B | — | — |
| 8TW9 | Cryo-EM structure of S. cerevisiae PolE-Ctf18-8-1-DNA | electron microscopy | B | — | 8 (best 0.79) |
| 8TWA | Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA-PolE-DNA complex | electron microscopy | B | — | 1 (best 0.76) |
| P25559 | AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein DCC1 (P25559) | predicted | A | — | — |
Ligands
- NO3 · Nitrate ion · in 2 records
Experiment against prediction
- 5MSN chain D against the predicted model P25559: TM-score 0.98, RMSD 0.94 Å
- 5MSN chain D against the predicted model P25559: TM-score 0.98, RMSD 0.94 Å
- 5MSN chain C against the predicted model P25559: TM-score 0.97, RMSD 1.07 Å
- 5MSN chain C against the predicted model P25559: TM-score 0.97, RMSD 1.07 Å
- 5MSN chain A against the predicted model P25559: TM-score 0.97, RMSD 1.16 Å
- 5MSN chain A against the predicted model P25559: TM-score 0.97, RMSD 1.16 Å
- 5MSN chain B against the predicted model P25559: TM-score 0.96, RMSD 1.34 Å
- 5MSN chain B against the predicted model P25559: TM-score 0.96, RMSD 1.34 Å
- 6S2E chain B against the predicted model P25559: TM-score 0.92, RMSD 2.01 Å
- 6S2E chain B against the predicted model P25559: TM-score 0.92, RMSD 2.01 Å
Elsewhere
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