UniProt P25101
Endoglucanase H,Endothelin-1 receptor (P25101)
Endoglucanase H,Endothelin-1 receptor (UniProt P25101), EC 3.2.1.4: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P25101
- Protein
- Endoglucanase H,Endothelin-1 receptor
- EC
- 3.2.1.4
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 2 records with a druggable one
Structures
3 records of P25101 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8XVI | Cryo-EM structure of ETAR bound with Endothelin1 | electron microscopy | R | — | 6 (best 0.76) |
| 8XVL | Cryo-EM structure of ETAR bound with Zibotentan | electron microscopy | R | A1D5L | 9 (best 0.72) |
| P25101 | AlphaFold monomer V2.0 prediction for endothelin-1 receptor (P25101) | predicted | A | — | — |
Ligands
- A1D5L · Zibotentan · in 1 record
Experiment against prediction
- 8XVI chain R against the predicted model P25101: TM-score 0.89, RMSD 2.49 Å
- 8XVL chain R against the predicted model P25101: TM-score 0.72, RMSD 2.08 Å
- 8XVL chain R against the predicted model P0ABE7: TM-score 0.25, RMSD 1.87 Å
- 8XVI chain R against the predicted model P16218: TM-score 0.26, RMSD 6.98 Å
- 8XVL chain R against the predicted model P16218: TM-score 0.25, RMSD 7.05 Å
Elsewhere
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