UniProt P25084
Transcriptional activator protein LasR (P25084)
Transcriptional activator protein LasR (UniProt P25084): 28 experimental structures on GenesisL1, 9 ligands bound, 55 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P25084
- Protein
- Transcriptional activator protein LasR
- Experimental structures
- 28
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 55 · 5 records with a druggable one
Structures
28 records of P25084 in the MolNFT archive: 28 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2UV0 | Structure of the P. aeruginosa LasR ligand-binding domain bound to its autoinducer | x-ray diffraction | E, F, G, H | — | — |
| 2UV0 | Structure of the P. aeruginosa lasr ligand-binding domain bound to its autoinducer | x-ray diffraction | E, F, G, H | — | — |
| 3IX3 | LasR-OC12 HSL complex | x-ray diffraction | A, B | — | — |
| 3IX3 | Lasr-OC12 hsl complex | x-ray diffraction | A, B | — | — |
| 3IX4 | LasR-TP1 complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3IX4 | Lasr-TP1 complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3IX8 | LasR-TP3 complex | x-ray diffraction | A, B, C, D | — | — |
| 3IX8 | Lasr-TP3 complex | x-ray diffraction | A, B, C, D | — | — |
| 3JPU | LasR-TP4 complex | x-ray diffraction | A, B, C, D, E | — | — |
| 3JPU | Lasr-TP4 complex | x-ray diffraction | A, B, C, D, E | — | — |
| 4NG2 | Crystal structure of LasR LBD-QslA complex from Pseudomonas aeruginosa | x-ray diffraction | A, B, C, D | — | — |
| 4NG2 | Crystal structure of lasr lbd-qsla complex from pseudomonas aeruginosa | x-ray diffraction | A, B, C, D | — | — |
| 6D6A | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 10 | x-ray diffraction | A, B, C, D, E, F, G, H | FXD | 17 (best 0.82) |
| 6D6A | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 10 | x-ray diffraction | A, B, C, D, E, F, G, H | FXD | — |
| 6D6B | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 11 | x-ray diffraction | A, B, C, D, E, F, G, H | FXS | 16 (best 0.82) |
| 6D6B | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 11 | x-ray diffraction | A, B, C, D, E, F, G, H | FXS | — |
| 6D6C | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 12 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | FYD | — |
| 6D6D | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 13 | x-ray diffraction | A, B | FY7 | — |
| 6D6L | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 14 | x-ray diffraction | A, B, C, D | FY4 | — |
| 6D6L | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 14 | x-ray diffraction | A, B, C, D | FY4 | — |
| 6D6M | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 15 | x-ray diffraction | A, B, C, D | TX7 | 7 (best 0.79) |
| 6D6M | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 15 | x-ray diffraction | A, B, C, D | TX7 | — |
| 6D6N | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 16 | x-ray diffraction | A, B, C, D | FXJ | — |
| 6D6O | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 17 | x-ray diffraction | A, B, C, D | FX7 | 8 (best 0.82) |
| 6D6O | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 17 | x-ray diffraction | A, B, C, D | FX7 | — |
| 6D6P | The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 19 | x-ray diffraction | A, B, C, D | FY1 | 7 (best 0.83) |
| 6D6P | The structure of ligand binding domain of lasr in complex with tp-1 homolog, compound 19 | x-ray diffraction | A, B, C, D | FY1 | — |
| P25084 | AlphaFold monomer V2.0 prediction for transcriptional activator protein lasr (P25084) | — | — | — |
Ligands
- FX7 · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl octanoate · in 2 records
- FXD · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl benzoate · in 2 records
- FXS · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 2-nitrobenzoate · in 2 records
- FY1 · N-{[3,5-dibromo-2-(methoxymethoxy)phenyl]methyl}-2-nitrobenzamide · in 2 records
- FY4 · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 4-chlorobenzoate · in 2 records
- TX7 · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 4-bromobenzoate · in 2 records
- FXJ · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 4-methoxybenzoate · in 1 record
- FY7 · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 2-cyanobenzoate · in 1 record
- FYD · 2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl) amino]methyl}phenyl 2-methoxybenzoate · in 1 record
Elsewhere
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