UniProt P24723
Protein kinase C eta type (P24723)
Protein kinase C eta type (UniProt P24723), EC 2.7.11.13: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P24723
- Protein
- Protein kinase C eta type
- EC
- 2.7.11.13
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
5 records of P24723 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3TXO | PKC eta kinase in complex with a naphthyridine | x-ray diffraction | A | — | — |
| 3TXO | PKC eta kinase in complex with a naphthyridine | x-ray diffraction | A | — | — |
| 8FP1 | PKCeta kinase domain in complex with compound 2 | x-ray diffraction | A | XXF | 3 (best 0.76) |
| 8FP3 | PKCeta kinase domain in complex with compound 11 | x-ray diffraction | A | Y3I | 4 (best 0.74) |
| P24723 | AlphaFold monomer V2.0 prediction for protein kinase C eta type (P24723) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8FP3 chain A against the predicted model P24723: TM-score 0.98, RMSD 0.88 Å
- 8FP1 chain A against the predicted model P24723: TM-score 0.98, RMSD 0.99 Å
- 3TXO chain A against the predicted model P24723: TM-score 0.95, RMSD 1.28 Å
- 3TXO chain A against the predicted model P24723: TM-score 0.95, RMSD 1.28 Å
Elsewhere
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