UniProt P24593
Insulin-like growth factor-binding protein 5 (P24593)
Insulin-like growth factor-binding protein 5 (UniProt P24593): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P24593
- Protein
- Insulin-like growth factor-binding protein 5
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
6 records of P24593 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BOE | Structure of the igf binding domain of the insulin-like growth factor-binding protein-5 (igfbp-5)… | solution nmr | A | — | — |
| 1BOE | Structure of the igf binding domain of the insulin-like growth factor- binding protein-5 (igfbp-5)… | solution nmr | A | — | — |
| 1H59 | Complex of IGFBP-5 with IGF-I | x-ray diffraction | B | — | — |
| 1H59 | Complex of igfbp-5 with igf-I | x-ray diffraction | B | — | — |
| 7UFG | Cryo-EM structure of PAPP-A in complex with IGFBP5 | electron microscopy | D, C | ZN | 5 (best 0.83) |
| P24593 | AlphaFold monomer V2.0 prediction for insulin-like growth factor- binding protein 5 (P24593) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 1H59 chain B against the predicted model P24593: TM-score 0.95, RMSD 0.50 Å
- 1H59 chain B against the predicted model P24593: TM-score 0.95, RMSD 0.50 Å
- 1BOE chain A against the predicted model P24593: TM-score 0.71, RMSD 1.57 Å
- 1BOE chain A against the predicted model P24593: TM-score 0.71, RMSD 1.57 Å
- 7UFG chain D against the predicted model P24593: TM-score 0.65, RMSD 1.23 Å
- 7UFG chain C against the predicted model P24593: TM-score 0.42, RMSD 0.91 Å
Elsewhere
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