UniProt P24268
Cathepsin D (P24268)
Cathepsin D (UniProt P24268), EC 3.4.23.5: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P24268
- Protein
- Cathepsin D
- EC
- 3.4.23.5
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
3 records of P24268 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UX4 | Crystal Structure of Rat Cathepsin D with (5S)-3-(5,6-dihydro-2H-pyran-3-yl)-1-fluoro… | x-ray diffraction | A, B | NAG, 3UT | 4 (best 0.75) |
| 5UX4 | Crystal structure of rat cathepsin D with (5S)-3-(5,6-dihydro-2H- pyran-3-yl)-1-fluoro… | x-ray diffraction | A, B | NAG, 3UT | — |
| P24268 | AlphaFold monomer V2.0 prediction for cathepsin D (P24268) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5UX4 chain B against the predicted model P24268: TM-score 0.99, RMSD 0.75 Å
- 5UX4 chain B against the predicted model P24268: TM-score 0.99, RMSD 0.75 Å
- 5UX4 chain A against the predicted model P24268: TM-score 0.99, RMSD 0.78 Å
- 5UX4 chain A against the predicted model P24268: TM-score 0.99, RMSD 0.78 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.