UniProt P24046
Gamma-aminobutyric acid receptor subunit rho-1 (P24046)
Gamma-aminobutyric acid receptor subunit rho-1 (UniProt P24046): 3 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P24046
- Protein
- Gamma-aminobutyric acid receptor subunit rho-1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 60 · 3 records with a druggable one
Structures
4 records of P24046 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OP9 | CryoEM structure of human rho1 GABAA receptor in complex with GABA | electron microscopy | A, B, C, D, E | ABU, NAG | 20 (best 0.81) |
| 8RH8 | CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in desensitized… | electron microscopy | A, E, B, C, D | ABU, NAG, CL | 20 (best 0.80) |
| 8RH9 | CryoEM structure of human rho1 GABAA receptor in complex with pregnenolone sulfate | electron microscopy | A, B, C, D, E | NAG, D10, D12, A8W, CL | 20 (best 0.86) |
| P24046 | AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit rho-1 (P24046) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8OP9 chain C against the predicted model P24046: TM-score 0.96, RMSD 1.48 Å
- 8OP9 chain D against the predicted model P24046: TM-score 0.96, RMSD 1.48 Å
- 8OP9 chain A against the predicted model P24046: TM-score 0.96, RMSD 1.48 Å
- 8OP9 chain B against the predicted model P24046: TM-score 0.96, RMSD 1.48 Å
- 8OP9 chain E against the predicted model P24046: TM-score 0.96, RMSD 1.48 Å
- 8RH8 chain C against the predicted model P24046: TM-score 0.94, RMSD 1.79 Å
- 8RH8 chain E against the predicted model P24046: TM-score 0.94, RMSD 1.79 Å
- 8RH8 chain D against the predicted model P24046: TM-score 0.94, RMSD 1.79 Å
- 8RH8 chain A against the predicted model P24046: TM-score 0.94, RMSD 1.79 Å
- 8RH8 chain B against the predicted model P24046: TM-score 0.94, RMSD 1.79 Å
Elsewhere
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