UniProt P24004
Peroxisomal ATPase PEX1 (P24004)
Peroxisomal ATPase PEX1 (UniProt P24004), EC 3.6.4.-: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 74 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P24004
- Protein
- Peroxisomal ATPase PEX1
- EC
- 3.6.4.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 74 · 4 records with a druggable one
Structures
4 records of P24004 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8C0V | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in single seam state | electron microscopy | A, C, E | ATP, MG, ADP | 19 (best 0.87) |
| 8C0W | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in twin seam state | electron microscopy | B, D, F | ATP, MG, ADP | 19 (best 0.87) |
| 8U0V | S. cerevisiae Pex1/Pex6 with 1 mM ATP | electron microscopy | A, C, E | ATP | 19 (best 0.86) |
| P24004 | AlphaFold monomer V2.0 prediction for peroxisomal ATPase PEX1 (P24004) | predicted | A | — | 17 (best 0.63) |
Ligands
Experiment against prediction
- 8U0V chain A against the predicted model P24004: TM-score 0.80, RMSD 4.79 Å
- 8C0V chain A against the predicted model P24004: TM-score 0.80, RMSD 4.87 Å
- 8C0V chain C against the predicted model P24004: TM-score 0.74, RMSD 5.63 Å
- 8C0W chain B against the predicted model P24004: TM-score 0.74, RMSD 5.68 Å
- 8C0W chain F against the predicted model P24004: TM-score 0.69, RMSD 6.63 Å
Elsewhere
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