UniProt P23644
Mitochondrial import receptor subunit TOM40 (P23644)
Mitochondrial import receptor subunit TOM40 (UniProt P23644): 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P23644
- Protein
- Mitochondrial import receptor subunit TOM40
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 43 · 3 records with a druggable one
Structures
10 records of P23644 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JNF | Cryo-EM structure of the translocator of the outer mitochondrial membrane | electron microscopy | A, F | 46E | — |
| 6UCU | Cryo-EM structure of the mitochondrial TOM complex from yeast (dimer) | electron microscopy | A, I | — | 17 (best 0.84) |
| 6UCU | Cryo-EM structure of the mitochondrial tom complex from yeast (dimer) | electron microscopy | A, I | — | — |
| 6UCV | Cryo-EM structure of the mitochondrial tom complex from yeast (tetramer) | electron microscopy | A, I, a, i | MC3 | — |
| 7E4H | Cryo-EM structure of the yeast mitochondrial SAM-Tom40 complex at 3.0 angstrom | electron microscopy | D | — | — |
| 7E4H | Cryo-EM structure of the yeast mitochondrial SAM-TOM40 complex at 3.0 ångström | electron microscopy | D | — | — |
| 7E4I | Cryo-EM structure of the yeast mitochondrial SAM-TOM40/TOM5/TOM6 complex at 3.0 ångström | electron microscopy | D | — | — |
| 7VKU | Cryo-EM structure of SAM-Tom40 intermediate complex | electron microscopy | X | — | 3 (best 0.70) |
| 8XKW | Structure of the TOM40 complex unannealed | electron microscopy | A, F | — | 19 (best 0.85) |
| P23644 | AlphaFold monomer V2.0 prediction for mitochondrial import receptor subunit TOM40 (P23644) | predicted | A | — | 4 (best 0.48) |
Ligands
Experiment against prediction
- 8XKW chain F against the predicted model P23644: TM-score 0.98, RMSD 1.02 Å
- 8XKW chain A against the predicted model P23644: TM-score 0.98, RMSD 1.02 Å
- 6UCU chain A against the predicted model P23644: TM-score 0.98, RMSD 1.01 Å
- 6UCU chain A against the predicted model P23644: TM-score 0.98, RMSD 1.01 Å
- 6UCU chain I against the predicted model P23644: TM-score 0.98, RMSD 1.01 Å
- 6UCV chain i against the predicted model P23644: TM-score 0.98, RMSD 1.02 Å
- 6UCV chain A against the predicted model P23644: TM-score 0.97, RMSD 1.19 Å
- 6UCV chain I against the predicted model P23644: TM-score 0.97, RMSD 1.19 Å
- 7E4H chain D against the predicted model P23644: TM-score 0.97, RMSD 1.27 Å
- 7E4H chain D against the predicted model P23644: TM-score 0.97, RMSD 1.27 Å
Elsewhere
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