UniProt P23301
Eukaryotic translation initiation factor 5A-1 (P23301)
Eukaryotic translation initiation factor 5A-1 (UniProt P23301): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P23301
- Protein
- Eukaryotic translation initiation factor 5A-1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 5 records with a druggable one
Structures
13 records of P23301 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ER0 | Crystal structure of the full length eIF5A from Saccharomyces cerevisiae | x-ray diffraction | A, B | — | — |
| 3ER0 | Crystal structure of the full length EIF5A from saccharomyces cerevisiae | x-ray diffraction | A, B | — | — |
| 5DGF | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA… | x-ray diffraction | f | MG | 1 (best 0.88) |
| 5GAK | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | electron microscopy | q | — | 1 (best 0.88) |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | BT | — | — |
| 6Q84 | Crystal structure of rangtp-PDR6-EIF5A export complex | x-ray diffraction | C, F | — | — |
| 6TNU | Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. | electron microscopy | eI | — | — |
| 7NRC | Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA… | electron microscopy | Ls | — | 2 (best 0.88) |
| 8AAF | Yeast RQC complex in state G | electron microscopy | v | — | — |
| 8AGZ | Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position | electron microscopy | v | — | 1 (best 0.87) |
| 8K2D | Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | electron microscopy | CE | — | 1 (best 0.86) |
| 8Y0U | dormant ribosome with STM1 | electron microscopy | 5 | — | — |
| P23301 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5A-1 (P23301) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 8AAF chain v against the predicted model P23301: TM-score 0.96, RMSD 0.96 Å
- 8AGZ chain v against the predicted model P23301: TM-score 0.96, RMSD 0.96 Å
- 6Q84 chain F against the predicted model P23301: TM-score 0.96, RMSD 0.93 Å
- 8K2D chain CE against the predicted model P23301: TM-score 0.96, RMSD 1.03 Å
- 6Q84 chain C against the predicted model P23301: TM-score 0.95, RMSD 0.98 Å
- 3ER0 chain B against the predicted model P23301: TM-score 0.95, RMSD 1.05 Å
- 3ER0 chain B against the predicted model P23301: TM-score 0.95, RMSD 1.05 Å
- 6TNU chain eI against the predicted model P23301: TM-score 0.92, RMSD 1.67 Å
- 3ER0 chain A against the predicted model P23301: TM-score 0.92, RMSD 1.59 Å
- 3ER0 chain A against the predicted model P23301: TM-score 0.92, RMSD 1.59 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.