UniProt P22621
Apical membrane antigen 1 (P22621)
Apical membrane antigen 1 (UniProt P22621): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22621
- Protein
- Apical membrane antigen 1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
4 records of P22621 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YXE | Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical… | solution nmr | A | — | — |
| 1YXE | Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical… | solution nmr | A | — | — |
| 8QU7 | Crystal structure of the Plasmodium falciparum Apical membrane antigen (AMA1) in complex with… | x-ray diffraction | E | NA | 3 (best 0.64) |
| P22621 | AlphaFold monomer V2.0 prediction for apical membrane antigen 1 (P22621) | predicted | A | — | — |
Ligands
- NA · Sodium ion · in 1 record
Experiment against prediction
- 8QU7 chain E against the predicted model P22621: TM-score 0.98, RMSD 0.94 Å
- 1YXE chain A against the predicted model P22621: TM-score 0.34, RMSD 5.33 Å
- 1YXE chain A against the predicted model P22621: TM-score 0.34, RMSD 5.33 Å
Elsewhere
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