UniProt P22411
Dipeptidyl peptidase 4 (P22411)
Dipeptidyl peptidase 4 (UniProt P22411), EC 3.4.14.5: 15 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22411
- Protein
- Dipeptidyl peptidase 4
- EC
- 3.4.14.5
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 1 record with a druggable one
Structures
16 records of P22411 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AJ8 | Porcine dipeptidyl peptidase IV (CD26) in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 2AJ8 | Porcine dipeptidyl peptidase IV (CD26) in complex with 7-benzyl-1,3… | x-ray diffraction | A, B, C, D | — | — |
| 2AJB | Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-Gly-L-Pro-L-Ile… | x-ray diffraction | A, B, C, D | — | — |
| 2AJB | Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-gly-L-pro-L-ile… | x-ray diffraction | A, B, C, D | — | — |
| 2AJC | Porcine dipeptidyl peptidase IV (CD26) in complex with 4-(2-Aminoethyl)-benzene sulphonyl fluoride… | x-ray diffraction | A, B, C, D | — | — |
| 2AJC | Porcine dipeptidyl peptidase IV (CD26) in complex with 4-(2- aminoethyl)-benzene sulphonyl fluoride… | x-ray diffraction | A, B, C, D | — | — |
| 2AJD | Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro) | x-ray diffraction | A, B, C, D | — | — |
| 2AJD | Porcine dipeptidyl peptidase IV (CD26) in complex with L-pro-boro-L- pro (boropro) | x-ray diffraction | A, B, C, D | — | — |
| 2BUA | Crystal Structure Of Porcine Dipeptidyl Peptidase IV (Cd26) in Complex With a Low Molecular Weight… | x-ray diffraction | A, B, C, D | — | — |
| 2BUA | Crystal structure of porcine dipeptidyl peptidase IV (CD26) in complex with a low molecular weight… | x-ray diffraction | A, B, C, D | — | — |
| 2BUC | Crystal Structure Of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a… | x-ray diffraction | A, B, C, D | — | — |
| 2BUC | Crystal structure of porcine dipeptidyl peptidase IV (CD26) in complex with a… | x-ray diffraction | A, B, C, D | — | — |
| 5LLS | Porcine dipeptidyl peptidase IV in complex with 8-(3-aminopiperidin-1-yl)-7-[(2-bromophenyl)methyl]… | x-ray diffraction | A, B, C, D | NAG, 6Z8, SO4 | 20 (best 0.73) |
| 5LLS | Porcine dipeptidyl peptidase IV in complex with 8-(3-aminopiperidin-1… | x-ray diffraction | A, B, C, D | NAG, 6Z8, SO4 | — |
| 7XNM | Structure of porcine dipeptidyl peptidase 4 inhibitory peptide complex | x-ray diffraction | A, B | NAG, BMA | — |
| P22411 | AlphaFold monomer V2.0 prediction for dipeptidyl peptidase 4 (P22411) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2AJC chain B against the predicted model P22411: TM-score 1.00, RMSD 0.44 Å
- 2AJC chain B against the predicted model P22411: TM-score 1.00, RMSD 0.44 Å
- 2AJ8 chain B against the predicted model P22411: TM-score 1.00, RMSD 0.46 Å
- 2AJ8 chain B against the predicted model P22411: TM-score 1.00, RMSD 0.46 Å
- 2BUC chain B against the predicted model P22411: TM-score 1.00, RMSD 0.46 Å
- 2BUC chain B against the predicted model P22411: TM-score 1.00, RMSD 0.46 Å
- 5LLS chain B against the predicted model P22411: TM-score 1.00, RMSD 0.49 Å
- 5LLS chain B against the predicted model P22411: TM-score 1.00, RMSD 0.49 Å
- 2BUC chain C against the predicted model P22411: TM-score 1.00, RMSD 0.49 Å
- 2BUC chain C against the predicted model P22411: TM-score 1.00, RMSD 0.49 Å
Elsewhere
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