UniProt P22137
Clathrin heavy chain (P22137)
Clathrin heavy chain (UniProt P22137): 3 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22137
- Protein
- Clathrin heavy chain
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 10 · 3 records with a druggable one
Structures
4 records of P22137 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9EX5 | Crystal structure of Yeast Clathrin Heavy Chain N-terminal domain bound to Epsin-5 peptide (LIDL) | x-ray diffraction | A, B, C | — | 5 (best 0.77) |
| 9EXT | Crystal structure of Yeast Clathrin Heavy Chain N-terminal domain bound to APL2/AP-1 Beta peptide… | x-ray diffraction | A, B | — | 4 (best 0.77) |
| 9EYT | Crystal structure of Yeast Clathrin Heavy Chain N-terminal domain bound to Epsin-1 peptide (LIDL) | x-ray diffraction | A | — | 1 (best 0.77) |
| P22137 | AlphaFold monomer V2.0 prediction for clathrin heavy chain (P22137) | predicted | A | — | — |
Experiment against prediction
- 9EYT chain A against the predicted model P22137: TM-score 0.99, RMSD 0.82 Å
- 9EX5 chain C against the predicted model P22137: TM-score 0.99, RMSD 0.86 Å
- 9EX5 chain B against the predicted model P22137: TM-score 0.99, RMSD 0.86 Å
- 9EX5 chain A against the predicted model P22137: TM-score 0.99, RMSD 0.86 Å
- 9EXT chain B against the predicted model P22137: TM-score 0.94, RMSD 1.27 Å
- 9EXT chain A against the predicted model P22137: TM-score 0.92, RMSD 1.20 Å
Elsewhere
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