UniProt P21693
ATP-dependent RNA helicase DbpA (P21693)
ATP-dependent RNA helicase DbpA (UniProt P21693), EC 3.6.4.13: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P21693
- Protein
- ATP-dependent RNA helicase DbpA
- EC
- 3.6.4.13
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 38 · 2 records with a druggable one
Structures
4 records of P21693 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BBB | Solution structure of C-terminal reca and rrm domains of the dead box helicase dbpa | solution nmr | A | — | — |
| 7PLI | DEAD-box helicase DbpA bound to single stranded RNA and ADP/BeF3 | x-ray diffraction | A, B, E, J, I, F | ADP, BEF, MG | 20 (best 0.83) |
| 7PMM | DEAD-box helicase DbpA in the active conformation bound to a ss/dsRNA junction and ADP/BeF3 | x-ray diffraction | A, B | ADP, BEF, MG | 18 (best 0.81) |
| P21693 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase dbpa (P21693) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7PLI chain I against the predicted model P21693: TM-score 0.96, RMSD 1.53 Å
- 7PLI chain J against the predicted model P21693: TM-score 0.96, RMSD 1.56 Å
- 7PLI chain E against the predicted model P21693: TM-score 0.96, RMSD 1.60 Å
- 7PMM chain B against the predicted model P21693: TM-score 0.96, RMSD 1.55 Å
- 7PLI chain F against the predicted model P21693: TM-score 0.96, RMSD 1.65 Å
- 7PMM chain A against the predicted model P21693: TM-score 0.96, RMSD 1.64 Å
- 7PLI chain A against the predicted model P21693: TM-score 0.96, RMSD 1.66 Å
- 7PLI chain B against the predicted model P21693: TM-score 0.95, RMSD 1.75 Å
- 7BBB chain A against the predicted model P21693: TM-score 0.88, RMSD 2.18 Å
Elsewhere
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