UniProt P21549
Serine--pyruvate aminotransferase (P21549)
Serine--pyruvate aminotransferase (UniProt P21549), EC 2.6.1.44, 2.6.1.51: 33 experimental structures on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P21549
- Protein
- Serine--pyruvate aminotransferase
- EC
- 2.6.1.44, 2.6.1.51
- Experimental structures
- 33
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 14 · 3 records with a druggable one
Structures
33 records of P21549 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H0C | The crystal structure of human alanine:glyoxylate aminotransferase | x-ray diffraction | A | — | — |
| 1H0C | The crystal structure of human ALANINE:GLYOXYLATE aminotransferase | x-ray diffraction | A | — | — |
| 1J04 | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | x-ray diffraction | A | — | — |
| 1J04 | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | x-ray diffraction | A | — | — |
| 2YOB | High resolution AGXT_M structure | x-ray diffraction | A, B | — | — |
| 2YOB | High resolution AGXT_M structure | x-ray diffraction | A, B | — | — |
| 3R9A | Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P | x-ray diffraction | A, C | — | — |
| 3R9A | Human alanine-glyoxylate aminotransferase in complex with the tpr domain of human PEX5P | x-ray diffraction | A, C | — | — |
| 4CBR | X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM) | x-ray diffraction | A | — | — |
| 4CBR | X-ray structure of the more stable human agxt triple mutant (AGXT_HEM) | x-ray diffraction | A | — | — |
| 4CBS | X-ray structure of quintuple mutant of human alanine glyoxylate aminotransferase, AGXT_RHEAM | x-ray diffraction | A | — | — |
| 4CBS | X-ray structure of quintuple mutant of human alanine glyoxylate aminotransferase, AGXT_RHEAM | x-ray diffraction | A | — | — |
| 4I8A | Alanine-glyoxylate aminotransferase variant S187F | x-ray diffraction | A, B, C, D | — | — |
| 4I8A | Alanine-glyoxylate aminotransferase variant S187F | x-ray diffraction | A, B, C, D | — | — |
| 4KXK | Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the TPR domain of human… | x-ray diffraction | A, C | — | — |
| 4KXK | Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the tpr domain of human… | x-ray diffraction | A, C | — | — |
| 4KYO | Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p | x-ray diffraction | A, C | — | — |
| 4KYO | Alanine-glyoxylate aminotransferase variant K390A in complex with the tpr domain of human PEX5P | x-ray diffraction | A, C | — | — |
| 5F9S | Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 1.7… | x-ray diffraction | A, B | PLP | 5 (best 0.73) |
| 5F9S | Crystal structure of human ALANINE:GLYOXYLATE aminotransferase major allele (agt-ma) at 1.7… | x-ray diffraction | A, B | — | — |
| 5HHY | Structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) showing X-Ray induced… | x-ray diffraction | A, B | PLR | 3 (best 0.68) |
| 5HHY | Structure of human ALANINE:GLYOXYLATE aminotransferase major allele (agt-ma) showing X-ray induced… | x-ray diffraction | A, B | — | — |
| 5LUC | Crystal structure of the D183N variant of human Alanine:Glyoxylate Aminotransferase major allele… | x-ray diffraction | A, B, E, G, M, N, S, T | PLP | — |
| 5LUC | Crystal structure of the D183N variant of human ALANINE:GLYOXYLATE aminotransferase major allele… | x-ray diffraction | A, B, E, G, M, N, S, T | PLP | — |
| 5OFY | Crystal structure of the D183N variant of human ALANINE:GLYOXYLATE aminotransferase major allele… | x-ray diffraction | A | PLP | — |
| 5OG0 | Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 2.5… | x-ray diffraction | A | PLP | 2 (best 0.44) |
| 5OG0 | Crystal structure of human ALANINE:GLYOXYLATE aminotransferase major allele (agt-ma) at 2.5… | x-ray diffraction | A | PLP | — |
| 6RV0 | Human ALANINE:GLYOXYLATE aminotransferase major allele (agt-ma); with pmp in the active site | x-ray diffraction | A | PMP | — |
| 6RV1 | human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) | x-ray diffraction | A | PLP | 4 (best 0.75) |
| 6RV1 | Human ALANINE:GLYOXYLATE aminotransferase major allele (agt-ma) | x-ray diffraction | A | PLP | — |
| 7NS7 | Human L-alanine:glyoxylate aminotransferase minor allele variant: AGXT-Mi (P11L-I340M) | x-ray diffraction | A, B | — | — |
| 7NS7 | Human L-ALANINE:GLYOXYLATE aminotransferase minor allele variant: agxt-mi (P11L-I340M) | x-ray diffraction | A, B | — | — |
| P21549 | AlphaFold monomer V2.0 prediction for serine--pyruvate aminotransferase (P21549) | — | — | — |
Ligands
Elsewhere
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