UniProt P21374
Pre-mRNA-splicing factor ISY1 (P21374)
Pre-mRNA-splicing factor ISY1 (UniProt P21374): 12 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P21374
- Protein
- Pre-mRNA-splicing factor ISY1
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 7 · 3 records with a druggable one
Structures
13 records of P21374 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GMK | Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution | electron microscopy | H | — | 4 (best 0.89) |
| 5GMK | Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström resolution | electron microscopy | H | — | — |
| 5LJ5 | Overall structure of the yeast spliceosome immediately after branching. | electron microscopy | G | — | — |
| 6J6G | Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | electron microscopy | H | — | 1 (best 0.80) |
| 6J6G | Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström | electron microscopy | H | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | electron microscopy | H | — | — |
| 6J6H | Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström | electron microscopy | H | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | electron microscopy | H | — | — |
| 6J6N | Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström | electron microscopy | H | — | — |
| 6J6Q | Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | electron microscopy | H | — | 2 (best 0.88) |
| 6J6Q | Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström | electron microscopy | H | — | — |
| 9DTR | Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution | electron microscopy | G | — | — |
| P21374 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ISY1 (P21374) | predicted | A | — | — |
Experiment against prediction
- 5LJ5 chain G against the predicted model P21374: TM-score 0.95, RMSD 1.03 Å
- 5GMK chain H against the predicted model P21374: TM-score 0.93, RMSD 1.03 Å
- 5GMK chain H against the predicted model P21374: TM-score 0.93, RMSD 1.03 Å
- 6J6Q chain H against the predicted model P21374: TM-score 0.93, RMSD 1.06 Å
- 6J6Q chain H against the predicted model P21374: TM-score 0.93, RMSD 1.06 Å
- 6J6N chain H against the predicted model P21374: TM-score 0.92, RMSD 0.97 Å
- 6J6N chain H against the predicted model P21374: TM-score 0.92, RMSD 0.97 Å
- 6J6H chain H against the predicted model P21374: TM-score 0.78, RMSD 0.27 Å
- 6J6H chain H against the predicted model P21374: TM-score 0.78, RMSD 0.27 Å
- 6J6G chain H against the predicted model P21374: TM-score 0.77, RMSD 1.79 Å
Elsewhere
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