UniProt P21127
Cyclin-dependent kinase 11B (P21127)
Cyclin-dependent kinase 11B (UniProt P21127), EC 2.7.11.22: 1 experimental structure and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P21127
- Protein
- Cyclin-dependent kinase 11B
- EC
- 2.7.11.22
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
2 records of P21127 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UKZ | CDK11 in complex with small molecule inhibitor OTS964 | x-ray diffraction | A, B, C, D, E, F | NK3, SO4 | 20 (best 0.68) |
| P21127 | AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 11B (P21127) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UKZ chain D against the predicted model P21127: TM-score 0.96, RMSD 1.30 Å
- 7UKZ chain F against the predicted model P21127: TM-score 0.96, RMSD 1.31 Å
- 7UKZ chain A against the predicted model P21127: TM-score 0.96, RMSD 1.33 Å
- 7UKZ chain B against the predicted model P21127: TM-score 0.96, RMSD 1.35 Å
- 7UKZ chain E against the predicted model P21127: TM-score 0.96, RMSD 1.43 Å
- 7UKZ chain C against the predicted model P21127: TM-score 0.96, RMSD 1.42 Å
Elsewhere
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