UniProt P20671
Histone H2A type 1-D (P20671)
Histone H2A type 1-D (UniProt P20671): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20671
- Protein
- Histone H2A type 1-D
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 2 records with a druggable one
Structures
8 records of P20671 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GT3 | Crystal structure of nucleosome particle in the presence of human testis-specific histone variant… | x-ray diffraction | C, G | MN | — |
| 5GT3 | Crystal structure of nucleosome particle in the presence of human testis-specific histone variant… | x-ray diffraction | C, G | — | — |
| 6KBB | Role of the DEF/Y motif of SWC5 in histone H2A.Z deposition | x-ray diffraction | C, A | — | — |
| 7EA8 | Human SETD2 bound to a nucleosome containing oncohistone mutations | electron microscopy | C, G | — | — |
| 7WLP | Epstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses | x-ray diffraction | A | — | — |
| 8H1T | Cryo-EM structure of BAP1-ASXL1 bound to chromatosome | electron microscopy | C, G | — | 11 (best 0.82) |
| 8YJM | Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single… | x-ray diffraction | G | — | 7 (best 0.71) |
| P20671 | AlphaFold monomer V2.0 prediction for histone H2A type 1-D (P20671) | predicted | A | — | — |
Ligands
- MN · Manganese (II) ion · in 1 record
Experiment against prediction
- 5GT3 chain G against the predicted model P20671: TM-score 0.97, RMSD 0.71 Å
- 5GT3 chain G against the predicted model P20671: TM-score 0.97, RMSD 0.71 Å
- 5GT3 chain C against the predicted model P20671: TM-score 0.96, RMSD 0.81 Å
- 5GT3 chain C against the predicted model P20671: TM-score 0.96, RMSD 0.81 Å
- 7EA8 chain G against the predicted model P20671: TM-score 0.95, RMSD 0.89 Å
- 7EA8 chain C against the predicted model P20671: TM-score 0.95, RMSD 0.92 Å
- 8H1T chain G against the predicted model P20671: TM-score 0.93, RMSD 1.40 Å
- 6KBB chain C against the predicted model P20671: TM-score 0.90, RMSD 1.40 Å
- 6KBB chain A against the predicted model P20671: TM-score 0.90, RMSD 1.44 Å
- 8H1T chain C against the predicted model P20671: TM-score 0.86, RMSD 1.33 Å
Elsewhere
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