UniProt P20338
RAS-related protein rab-4A (P20338)
RAS-related protein rab-4A (UniProt P20338): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20338
- Protein
- RAS-related protein rab-4A
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of P20338 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YU9 | GppNHp-Bound Rab4A | x-ray diffraction | A | — | — |
| 1YU9 | Gppnhp-bound RAB4A | x-ray diffraction | A | — | — |
| 1Z0K | Structure of GTP-Bound Rab4Q67L GTPase in complex with the central Rab binding domain of Rabenosyn-5 | x-ray diffraction | A, C | — | — |
| 1Z0K | Structure of GTP-bound RAB4Q67L GTPase in complex with the central rab binding domain of rabenosyn-5 | x-ray diffraction | A, C | — | — |
| 2BMD | high resolution structure of GDP-bound human Rab4a | x-ray diffraction | A | — | — |
| 2BMD | High resolution structure of GDP-bound human RAB4A | x-ray diffraction | A | — | — |
| 2BME | high resolution structure of GppNHp-bound human Rab4a | x-ray diffraction | A, B, C, D | — | — |
| 2BME | High resolution structure of gppnhp-bound human RAB4A | x-ray diffraction | A, B, C, D | — | — |
| P20338 | AlphaFold monomer V2.0 prediction for RAS-related protein rab-4A (P20338) | predicted | A | — | 2 (best 0.50) |
Experiment against prediction
- 2BME chain B against the predicted model P20338: TM-score 0.98, RMSD 0.65 Å
- 2BME chain B against the predicted model P20338: TM-score 0.98, RMSD 0.65 Å
- 2BME chain C against the predicted model P20338: TM-score 0.98, RMSD 0.70 Å
- 2BME chain C against the predicted model P20338: TM-score 0.98, RMSD 0.70 Å
- 1Z0K chain A against the predicted model P20338: TM-score 0.98, RMSD 0.75 Å
- 1Z0K chain A against the predicted model P20338: TM-score 0.98, RMSD 0.75 Å
- 1Z0K chain C against the predicted model P20338: TM-score 0.98, RMSD 0.75 Å
- 1Z0K chain C against the predicted model P20338: TM-score 0.98, RMSD 0.75 Å
- 2BME chain A against the predicted model P20338: TM-score 0.98, RMSD 0.82 Å
- 2BME chain A against the predicted model P20338: TM-score 0.98, RMSD 0.82 Å
Elsewhere
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