UniProt P20095
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 (P20095)
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 (UniProt P20095), EC 3.6.4.13: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and…
- UniProt
- P20095
- Protein
- Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2
- EC
- 3.6.4.13
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 2 records with a druggable one
Structures
5 records of P20095 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | Y | MG, ADP | — |
| 5LQW | yeast activated spliceosome | electron microscopy | O | — | — |
| 5LQW | Yeast activated spliceosome | electron microscopy | O | — | — |
| 7DCO | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5… | electron microscopy | x | — | 1 (best 0.88) |
| P20095 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ATP- dependent RNA helicase-like… | predicted | A | — | 9 (best 0.80) |
Ligands
Experiment against prediction
- 5GM6 chain Y against the predicted model P20095: TM-score 0.95, RMSD 2.11 Å
- 7DCO chain x against the predicted model P20095: TM-score 0.93, RMSD 2.54 Å
- 5LQW chain O against the predicted model P20095: TM-score 0.78, RMSD 4.49 Å
- 5LQW chain O against the predicted model P20095: TM-score 0.78, RMSD 4.49 Å
Elsewhere
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