UniProt P20036
HLA class II histocompatibility antigen, DP alpha 1 chain (P20036)
HLA class II histocompatibility antigen, DP alpha 1 chain (UniProt P20036): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P20036
- Protein
- HLA class II histocompatibility antigen, DP alpha 1 chain
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 19 · 1 record with a druggable one
Structures
15 records of P20036 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LQZ | Crystal Structure of HLA-DP2 | x-ray diffraction | A | — | — |
| 3LQZ | Crystal structure of HLA-DP2 | x-ray diffraction | A | — | — |
| 4P4K | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between allergic hypersensitivity… | x-ray diffraction | A, E | — | — |
| 4P4K | Structural basis of chronic beryllium disease: bridging the gap between allergic hypersensitivity… | x-ray diffraction | A, E | — | — |
| 4P4R | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity… | x-ray diffraction | A, C | — | — |
| 4P4R | Structural basis of chronic beryllium disease: bridging the gap between allergic hypersensitivity… | x-ray diffraction | A, C | — | — |
| 4P57 | MHC TCR peptide complex | x-ray diffraction | A, C | — | — |
| 4P57 | MHC TCR peptide complex | x-ray diffraction | A, C | — | — |
| 4P5K | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity | x-ray diffraction | A, D | — | — |
| 4P5K | Structural basis of chronic beryllium disease: bridging the gap between allergy and autoimmunity | x-ray diffraction | A, D | — | — |
| 4P5M | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity… | x-ray diffraction | A, C, E, G | — | — |
| 4P5M | Structural basis of chronic beryllium disease: bridging the gap between allergic hypersensitivity… | x-ray diffraction | A, C, E, G | — | — |
| 7T2C | Crystal structure of the B5 TCR in complex with HLA-DP4-Ply | x-ray diffraction | A | NAG | 7 (best 0.47) |
| 7T2D | Crystal structure of the B1 TCR in complex with HLA-DP4-Ply | x-ray diffraction | A, F, K, P | NAG | 12 (best 0.54) |
| P20036 | AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dp alpha 1 chain… | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 4P5M chain C against the predicted model P20036: TM-score 0.96, RMSD 1.23 Å
- 4P57 chain C against the predicted model P20036: TM-score 0.96, RMSD 1.05 Å
- 4P57 chain C against the predicted model P20036: TM-score 0.96, RMSD 1.05 Å
- 7T2C chain A against the predicted model P20036: TM-score 0.96, RMSD 0.97 Å
- 4P57 chain A against the predicted model P20036: TM-score 0.96, RMSD 1.06 Å
- 4P57 chain A against the predicted model P20036: TM-score 0.96, RMSD 1.06 Å
- 4P5M chain E against the predicted model P20036: TM-score 0.96, RMSD 0.98 Å
- 4P4K chain A against the predicted model P20036: TM-score 0.96, RMSD 1.04 Å
- 4P4K chain A against the predicted model P20036: TM-score 0.96, RMSD 1.04 Å
- 4P5M chain A against the predicted model P20036: TM-score 0.96, RMSD 0.99 Å
Elsewhere
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