UniProt P18708
Vesicle-fusing ATPase (P18708)
Vesicle-fusing ATPase (UniProt P18708): 27 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18708
- Protein
- Vesicle-fusing ATPase
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 1 record with a druggable one
Structures
28 records of P18708 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D2N | D2 domain of N-ethylmaleimide-sensitive fusion protein | x-ray diffraction | A | — | — |
| 1D2N | D2 domain of N-ethylmaleimide-sensitive fusion protein | x-ray diffraction | A | — | — |
| 1NSF | D2 hexamerization domain of N-ethylmaleimide sensitive factor (nsf) | x-ray diffraction | A | — | — |
| 1NSF | D2 hexamerization domain of N-ethylmaleimide sensitive factor (nsf) | x-ray diffraction | A | — | — |
| 1QCS | N-terminal domain of N-ethylmaleimide sensitive factor (nsf) | x-ray diffraction | A | — | — |
| 1QCS | N-terminal domain of N-ethylmaleimide sensitive factor (nsf) | x-ray diffraction | A | — | — |
| 1QDN | Amino terminal domain of the N-ethylmaleimide sensitive fusion protein (nsf) | x-ray diffraction | A, B, C | — | — |
| 1QDN | Amino terminal domain of the N-ethylmaleimide sensitive fusion protein (nsf) | x-ray diffraction | A, B, C | — | — |
| 3J94 | Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron… | electron microscopy | A, B, C, D, E, F | — | — |
| 3J94 | Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron… | electron microscopy | A, B, C, D, E, F | — | — |
| 3J95 | Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron… | electron microscopy | A, B, C, D, E, F | — | — |
| 3J95 | Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron… | electron microscopy | A, B, C, D, E, F | — | — |
| 3J96 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J96 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (state I) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J97 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J97 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (state II) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J98 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J98 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (state iiia) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J99 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb) | electron microscopy | A, B, C, D, E, F | — | — |
| 3J99 | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (state iiib) | electron microscopy | A, B, C, D, E, F | — | — |
| 6IP2 | NSF-D1D2 part in the whole 20S complex | electron microscopy | B, C, D, E, F, A | ATP | — |
| 6IP2 | Nsf-D1D2 part in the whole 20S complex | electron microscopy | B, C, D, E, F, A | ATP | — |
| 6MDM | The 20S supercomplex engaging the snap-25 N-terminus (class 1) | electron microscopy | A, B, C, D, E, F | ATP, ADP | — |
| 6MDN | The 20S supercomplex engaging the SNAP-25 N-terminus (class 2) | electron microscopy | A, B, C, D, E, F | ATP, ADP | — |
| 6MDN | The 20S supercomplex engaging the snap-25 N-terminus (class 2) | electron microscopy | A, B, C, D, E, F | ATP, ADP | — |
| 6MDO | The D1 and D2 domain rings of nsf engaging the snap-25 N-terminus within the 20S supercomplex… | electron microscopy | A, B, C, D, E, F | ATP, ADP | — |
| 6MDP | The D1 and D2 domain rings of nsf engaging the snap-25 N-terminus within the 20S supercomplex… | electron microscopy | A, B, C, D, E, F | ADP, ATP | — |
| P18708 | AlphaFold monomer V2.0 prediction for vesicle-fusing ATPase (P18708) | predicted | A | — | 9 (best 0.66) |
Ligands
Experiment against prediction
- 1D2N chain A against the predicted model P18708: TM-score 0.98, RMSD 0.86 Å
- 1D2N chain A against the predicted model P18708: TM-score 0.98, RMSD 0.86 Å
- 1QCS chain A against the predicted model P18708: TM-score 0.98, RMSD 0.77 Å
- 1QCS chain A against the predicted model P18708: TM-score 0.98, RMSD 0.77 Å
- 1NSF chain A against the predicted model P18708: TM-score 0.98, RMSD 1.25 Å
- 1NSF chain A against the predicted model P18708: TM-score 0.98, RMSD 1.25 Å
- 1QDN chain A against the predicted model P18708: TM-score 0.97, RMSD 0.92 Å
- 1QDN chain A against the predicted model P18708: TM-score 0.97, RMSD 0.92 Å
- 3J94 chain C against the predicted model P18708: TM-score 0.97, RMSD 1.30 Å
- 3J94 chain C against the predicted model P18708: TM-score 0.97, RMSD 1.30 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.