UniProt P18510
P18510
P18510 (UniProt P18510): 10 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18510
- Experimental structures
- 10
- Predicted models
- 1
Structures
11 records of P18510 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ILR | Crystal structure of the interleukin-1 receptor antagonist | x-ray diffraction | 1, 2 | — | — |
| 1ILR | Crystal structure of the interleukin-1 receptor antagonist | x-ray diffraction | 1, 2 | — | — |
| 1ILT | X-ray structure of interleukin-1 receptor antagonist at 2.0 ångströms resolution | x-ray diffraction | A, B | — | — |
| 1ILT | X-ray structure of interleukin-1 receptor antagonist at 2.0 ångströms resolution | x-ray diffraction | A, B | — | — |
| 1IRA | Complex of the interleukin-1 receptor with the interleukin-1 receptor antagonist (IL1RA) | x-ray diffraction | X | — | — |
| 1IRA | Complex of the interleukin-1 receptor with the interleukin-1 receptor antagonist (IL1RA) | x-ray diffraction | X | — | — |
| 1IRP | Solution structure of human interleukin-1 receptor antagonist protein | solution nmr | A | — | — |
| 1IRP | Solution structure of human interleukin-1 receptor antagonist protein | solution nmr | A | — | — |
| 2IRT | Initial crystallographic analyses of a recombinant interleukin-1 receptor antagonist protein | x-ray diffraction | A, B | — | — |
| 2IRT | Initial crystallographic analyses of a recombinant interleukin-1 receptor antagonist protein | x-ray diffraction | A, B | — | — |
| P18510 | AlphaFold monomer V2.0 prediction for interleukin-1 receptor antagonist protein (P18510) | predicted | A | — | — |
Experiment against prediction
- 1IRA chain X against the predicted model P18510: TM-score 0.99, RMSD 0.57 Å
- 1IRA chain X against the predicted model P18510: TM-score 0.99, RMSD 0.57 Å
- 1ILR chain 1 against the predicted model P18510: TM-score 0.98, RMSD 0.64 Å
- 1ILR chain 1 against the predicted model P18510: TM-score 0.98, RMSD 0.64 Å
- 1ILT chain A against the predicted model P18510: TM-score 0.98, RMSD 0.64 Å
- 1ILT chain A against the predicted model P18510: TM-score 0.98, RMSD 0.64 Å
- 1ILR chain 2 against the predicted model P18510: TM-score 0.98, RMSD 0.73 Å
- 1ILR chain 2 against the predicted model P18510: TM-score 0.98, RMSD 0.73 Å
- 2IRT chain A against the predicted model P18510: TM-score 0.92, RMSD 1.55 Å
- 2IRT chain A against the predicted model P18510: TM-score 0.92, RMSD 1.55 Å
Elsewhere
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