UniProt P18508
P18508
P18508 (UniProt P18508): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18508
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
Structures
6 records of P18508 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2PR9 | Mu2 adaptin subunit (AP50) of AP2 adaptor (second domain), complexed with GABAA receptor-gamma2… | x-ray diffraction | P | — | — |
| 2PR9 | MU2 adaptin subunit (AP50) of AP2 adaptor (second domain), complexed with gabaa receptor-GAMMA2… | x-ray diffraction | P | — | — |
| 6DW0 | Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor… | electron microscopy | D | BMA, MAN | — |
| 6DW0 | Cryo-EM structure of the benzodiazepine-sensitive ALPHA1BETA1GAMMA2S tri-heteromeric gabaa receptor… | electron microscopy | D | BMA, MAN | — |
| 6DW1 | Cryo-EM structure of the benzodiazepine-sensitive ALPHA1BETA1GAMMA2S tri-heteromeric gabaa receptor… | electron microscopy | D | BMA, MAN | — |
| P18508 | AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit gamma-2 (P18508) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6DW1 chain D against the predicted model P18508: TM-score 0.97, RMSD 0.82 Å
- 6DW0 chain D against the predicted model P18508: TM-score 0.96, RMSD 1.18 Å
- 6DW0 chain D against the predicted model P18508: TM-score 0.96, RMSD 1.18 Å
- 2PR9 chain P against the predicted model P18508: TM-score 0.35, RMSD 1.85 Å
- 2PR9 chain P against the predicted model P18508: TM-score 0.35, RMSD 1.85 Å
Elsewhere
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