UniProt P18421
Proteasome subunit beta type-1 (P18421)
Proteasome subunit beta type-1 (UniProt P18421), EC 3.4.25.1: 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18421
- Protein
- Proteasome subunit beta type-1
- EC
- 3.4.25.1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of P18421 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | 6 | — | — |
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | 6 | — | — |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | 6 | — | — |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | 6 | — | — |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | 6 | — | — |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | 6 | — | — |
| 6EPF | Ground state 26S proteasome (GS1) | electron microscopy | 6 | — | — |
| 6TU3 | Rat 20S proteasome | electron microscopy | M, a | — | — |
| P18421 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-1 (P18421) | predicted | A | — | 1 (best 0.30) |
Experiment against prediction
- 6TU3 chain M against the predicted model P18421: TM-score 0.99, RMSD 0.55 Å
- 6EPE chain 6 against the predicted model P18421: TM-score 0.87, RMSD 2.32 Å
- 6EPE chain 6 against the predicted model P18421: TM-score 0.87, RMSD 2.32 Å
- 6EPD chain 6 against the predicted model P18421: TM-score 0.86, RMSD 2.31 Å
- 6EPD chain 6 against the predicted model P18421: TM-score 0.86, RMSD 2.31 Å
- 6EPC chain 6 against the predicted model P18421: TM-score 0.85, RMSD 2.40 Å
- 6EPC chain 6 against the predicted model P18421: TM-score 0.85, RMSD 2.40 Å
- 6EPF chain 6 against the predicted model P18421: TM-score 0.84, RMSD 2.53 Å
Elsewhere
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