UniProt P18203
FK506 binding protein (P18203)
FK506 binding protein (UniProt P18203), EC 5.2.1.8: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18203
- Protein
- FK506 binding protein
- EC
- 5.2.1.8
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 0 records with a druggable one
Structures
5 records of P18203 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FKK | Atomic structure of FKBP12, an immunophilin binding protein | x-ray diffraction | A | SO4 | 1 (best 0.37) |
| 1FKK | Atomic structure of FKBP12, an immunophilin binding protein | x-ray diffraction | A | SO4 | 1 (best 0.37) |
| 1FKL | Atomic structure of FKBP12-rapaymycin, an immunophilin-immunosuppressant complex | x-ray diffraction | A | RAP | 1 (best 0.43) |
| 1FKL | Atomic structure of FKBP12-rapaymycin, an immunophilin- immunosuppressant complex | x-ray diffraction | A | RAP | 1 (best 0.43) |
| P18203 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP1A (P18203) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1FKK chain A against the predicted model P18203: TM-score 0.99, RMSD 0.44 Å
- 1FKK chain A against the predicted model P18203: TM-score 0.99, RMSD 0.44 Å
- 1FKL chain A against the predicted model P18203: TM-score 0.98, RMSD 0.60 Å
- 1FKL chain A against the predicted model P18203: TM-score 0.98, RMSD 0.60 Å
Elsewhere
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