UniProt P18146
Early growth response protein 1 (P18146)
Early growth response protein 1 (UniProt P18146): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18146
- Protein
- Early growth response protein 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of P18146 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4R2A | Egr1/Zif268 zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4R2A | EGR1/ZIF268 zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4R2C | Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA | x-ray diffraction | A | — | — |
| 4R2C | EGR1/ZIF268 zinc fingers in complex with hydroxymethylated DNA | x-ray diffraction | A | — | — |
| 4R2D | Egr1/Zif268 zinc fingers in complex with formylated DNA | x-ray diffraction | A | — | — |
| 4R2D | EGR1/ZIF268 zinc fingers in complex with formylated DNA | x-ray diffraction | A | — | — |
| 4X9J | EGR-1 with Doubly Methylated DNA | x-ray diffraction | A | ZN | 2 (best 0.60) |
| 4X9J | Egr-1 with doubly methylated DNA | x-ray diffraction | A | — | — |
| P18146 | AlphaFold monomer V2.0 prediction for early growth response protein 1 (P18146) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 4R2A chain A against the predicted model P18146: TM-score 0.95, RMSD 0.85 Å
- 4R2A chain A against the predicted model P18146: TM-score 0.95, RMSD 0.85 Å
- 4R2C chain A against the predicted model P18146: TM-score 0.94, RMSD 0.92 Å
- 4R2C chain A against the predicted model P18146: TM-score 0.94, RMSD 0.92 Å
- 4X9J chain A against the predicted model P18146: TM-score 0.93, RMSD 0.95 Å
- 4X9J chain A against the predicted model P18146: TM-score 0.93, RMSD 0.95 Å
- 4R2D chain A against the predicted model P18146: TM-score 0.93, RMSD 0.99 Å
- 4R2D chain A against the predicted model P18146: TM-score 0.93, RMSD 0.99 Å
Elsewhere
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