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UniProt P17858

ATP-dependent 6-phosphofructokinase, liver type (P17858)

ATP-dependent 6-phosphofructokinase, liver type (UniProt P17858), EC 2.7.1.11: 3 experimental structures on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P17858
Protein
ATP-dependent 6-phosphofructokinase, liver type
EC
2.7.1.11
Experimental structures
3
Predicted models
0
Ligands
4
Pockets
20 · 1 record with a druggable one

Structures

3 records of P17858 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7LW1Human phosphofructokinase-1 liver type bound to activator NA-11electron microscopyA, D, E, FYG1, FBP, F6P, ADP20 (best 0.83)
7LW1Human phosphofructokinase-1 liver type bound to activator na-11electron microscopyA, D, E, FYG1, FBP, F6P, ADP—
P17858AlphaFold monomer V2.0 prediction for ATP-dependent 6-phosphofructokinase, liver type (P17858)———

Ligands

  • ADP · Adenosine-5'-diphosphate · in 2 records
  • F6P · 6-O-phosphono-beta-D-fructofuranose · in 2 records
  • FBP · 1,6-di-O-phosphono-beta-D-fructofuranose · in 2 records
  • YG1 · N-{(11S)-2-[2-(5-hydroxypent-1-yn-1-yl)phenyl]-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl}acetamide · in 2 records

Elsewhere

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