UniProt P17643
5,6-dihydroxyindole-2-carboxylic acid oxidase (P17643)
5,6-dihydroxyindole-2-carboxylic acid oxidase (UniProt P17643), EC 1.14.18.-: 17 experimental structures on GenesisL1, 10 ligands bound, 102 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P17643
- Protein
- 5,6-dihydroxyindole-2-carboxylic acid oxidase
- EC
- 1.14.18.-
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 102 · 6 records with a druggable one
Structures
17 records of P17643 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5M8L | Crystal structure of human tyrosinase related protein 1 | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN | 18 (best 0.78) |
| 5M8L | Crystal structure of human tyrosinase related protein 1 | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN | — |
| 5M8M | Crystal structure of human tyrosinase related protein 1 in complex with kojic acid | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN, KOJ | — |
| 5M8M | Crystal structure of human tyrosinase related protein 1 in complex with kojic acid | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN, KOJ | — |
| 5M8N | Crystal structure of human tyrosinase related protein 1 in complex with mimosine | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN, MMS | — |
| 5M8O | Crystal structure of human tyrosinase related protein 1 in complex with tropolone | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, 0TR, ZN | 20 (best 0.79) |
| 5M8O | Crystal structure of human tyrosinase related protein 1 in complex with tropolone | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, 0TR, ZN | — |
| 5M8P | Crystal structure of human tyrosinase related protein 1 in complex with tyrosine | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, TYR, ZN | 20 (best 0.79) |
| 5M8P | Crystal structure of human tyrosinase related protein 1 in complex with tyrosine | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN | — |
| 5M8Q | Crystal structure of human tyrosinase related protein 1 mutant (T391V- R374S-Y362F) in complex with… | x-ray diffraction | A, B, C, D | NAG, FUC, ZN, KOJ | — |
| 5M8R | Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with mimosine | x-ray diffraction | A, B, C, D | NAG, FUC, ZN, MMS | 20 (best 0.80) |
| 5M8R | Crystal structure of human tyrosinase related protein 1 (T391V-R374S- Y362F) in complex with… | x-ray diffraction | A, B, C, D | NAG, FUC, ZN, MMS | — |
| 5M8S | Crystal structure of human tyrosinase related protein 1 mutant (T391V-R374S-Y362F) in complex with… | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, URS, ZN | 20 (best 0.80) |
| 5M8S | Crystal structure of human tyrosinase related protein 1 mutant (T391V- R374S-Y362F) in complex with… | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, URS, ZN | — |
| 5M8T | Crystal structure of human tyrosinase related protein 1 (T391V-R374S- Y362F) in complex with… | x-ray diffraction | A, B, C, D | NAG, FUC, MAN, ZN, 0TR | — |
| 9EY5 | Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with… | x-ray diffraction | A | NAG, FUC, OTY, ZN | 4 (best 0.73) |
| P17643 | AlphaFold monomer V2.0 prediction for 5,6-dihydroxyindole-2-carboxylic acid oxidase (P17643) | — | — | — |
Ligands
- FUC · alpha-L-fucopyranose · in 16 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 16 records
- ZN · Zinc ion · in 16 records
- MAN · alpha-D-mannopyranose · in 12 records
- 0TR · 2-hydroxycyclohepta-2,4,6-trien-1-one · in 3 records
- KOJ · 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one · in 3 records
- MMS · Mimosine · in 3 records
- URS · N-phenylthiourea · in 2 records
- OTY · 2-hydroxy-L-tyrosine · in 1 record
- TYR · Tyrosine · in 1 record
Elsewhere
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