UniProt P17605

ATP synthase F(0) complex subunit C1, mitochondrial (P17605)

ATP synthase F(0) complex subunit C1, mitochondrial (UniProt P17605): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction…

UniProt: P17605
Protein: ATP synthase F(0) complex subunit C1, mitochondrial
Experimental structures: 4
Predicted models: 1
Ligands: 3
Pockets: 9 · 2 records with a druggable one

Structures

5 records of P17605 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6TT7	Ovine ATP synthase 1a state	electron microscopy	1, 2, 3, 4, 5, 6, 7, 8	P5S, LHG, S12	3 (best 0.90)
6TT7	Ovine ATP synthase 1A state	electron microscopy	1, 2, 3, 4, 5, 6, 7, 8	LHG	—
6ZA9	Fo domain of Ovine ATP synthase	electron microscopy	1, 2, 3, 4, 5, 6, 7, 8	LHG, S12	6 (best 0.90)
6ZA9	Fo domain of ovine ATP synthase	electron microscopy	1, 2, 3, 4, 5, 6, 7, 8	LHG	—
P17605	AlphaFold monomer V2.0 prediction for ATP synthase F(0) complex subunit C1, mitochondrial (P17605)	predicted	A	—	—

Ligands

LHG · 1,2-dipalmitoyl-phosphatidyl-glycerole · in 4 records
S12 · O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine · in 2 records
P5S · O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy) propyl]oxy}(hydroxy)phosphoryl]-L-serine · in 1 record

Experiment against prediction

6TT7 chain 6 against the predicted model P17605: TM-score 0.96, RMSD 0.65 Å
6TT7 chain 6 against the predicted model P17605: TM-score 0.96, RMSD 0.65 Å
6ZA9 chain 6 against the predicted model P17605: TM-score 0.95, RMSD 0.67 Å
6ZA9 chain 6 against the predicted model P17605: TM-score 0.95, RMSD 0.67 Å
6ZA9 chain 7 against the predicted model P17605: TM-score 0.95, RMSD 0.73 Å
6ZA9 chain 7 against the predicted model P17605: TM-score 0.95, RMSD 0.73 Å
6ZA9 chain 5 against the predicted model P17605: TM-score 0.95, RMSD 0.73 Å
6ZA9 chain 5 against the predicted model P17605: TM-score 0.95, RMSD 0.73 Å
6ZA9 chain 8 against the predicted model P17605: TM-score 0.95, RMSD 0.75 Å
6ZA9 chain 8 against the predicted model P17605: TM-score 0.95, RMSD 0.75 Å

Elsewhere

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