UniProt P16675
Lysosomal protective protein (P16675)
Lysosomal protective protein (UniProt P16675), EC 3.4.16.5: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P16675
- Protein
- Lysosomal protective protein
- EC
- 3.4.16.5
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 2 records with a druggable one
Structures
3 records of P16675 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7KDV | Murine core lysosomal multienzyme complex (LMC) composed of acid beta-galactosidase (GLB1) and… | electron microscopy | B, D, F, H, J, L | NAG | 12 (best 0.79) |
| 7KDV | Murine core lysosomal multienzyme complex (lmc) composed of acid beta- galactosidase (GLB1) and… | electron microscopy | B, D, F, H, J, L | NAG | — |
| P16675 | AlphaFold monomer V2.0 prediction for lysosomal protective protein (P16675) | predicted | A | — | 5 (best 0.72) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 7KDV chain H against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain L against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain D against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain J against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain B against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain F against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
- 7KDV chain B against the predicted model P16675: TM-score 0.98, RMSD 1.05 Å
Elsewhere
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