UniProt P16621
Tyrosine-protein phosphatase Lar (P16621)
Tyrosine-protein phosphatase Lar (UniProt P16621), EC 3.1.3.48: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P16621
- Protein
- Tyrosine-protein phosphatase Lar
- EC
- 3.1.3.48
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
7 records of P16621 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YD1 | Crystal structure of the N-terminal Ig1-2 module of Drosophila Receptor Protein Tyrosine… | x-ray diffraction | A | — | — |
| 2YD1 | Crystal structure of the N-terminal IG1-2 module of drosophila receptor protein tyrosine… | x-ray diffraction | A | — | — |
| 3PXJ | Tandem Ig repeats of Dlar | x-ray diffraction | A, B, C, D | — | — |
| 3PXJ | Tandem ig repeats of dlar | x-ray diffraction | A, B, C, D | — | — |
| 6X38 | Crystal structure of the FN5 domain of Drosophila Lar | x-ray diffraction | A | ZN | — |
| 6X38 | Crystal structure of the FN5 domain of drosophila lar | x-ray diffraction | A | ZN | — |
| P16621 | AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase lar (P16621) | predicted | A | — | 20 (best 0.76) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 3PXJ chain C against the predicted model P16621: TM-score 0.97, RMSD 0.90 Å
- 3PXJ chain C against the predicted model P16621: TM-score 0.97, RMSD 0.90 Å
- 3PXJ chain D against the predicted model P16621: TM-score 0.97, RMSD 0.98 Å
- 3PXJ chain D against the predicted model P16621: TM-score 0.97, RMSD 0.98 Å
- 3PXJ chain A against the predicted model P16621: TM-score 0.96, RMSD 1.06 Å
- 3PXJ chain A against the predicted model P16621: TM-score 0.96, RMSD 1.06 Å
- 2YD1 chain A against the predicted model P16621: TM-score 0.94, RMSD 1.42 Å
- 2YD1 chain A against the predicted model P16621: TM-score 0.94, RMSD 1.42 Å
- 6X38 chain A against the predicted model P16621: TM-score 0.91, RMSD 1.26 Å
- 6X38 chain A against the predicted model P16621: TM-score 0.91, RMSD 1.26 Å
Elsewhere
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