UniProt P16455
Methylated-DNA--protein-cysteine methyltransferase,Cell division control protein 12 (P16455)
Methylated-DNA--protein-cysteine methyltransferase,Cell division control protein 12 (UniProt P16455), EC 2.1.1.63: 18 experimental structures on GenesisL1, 37 pockets. Binding sites, pockets, druggability and 3D structures in…
- UniProt
- P16455
- Protein
- Methylated-DNA--protein-cysteine methyltransferase,Cell division control…
- EC
- 2.1.1.63
- Experimental structures
- 18
- Predicted models
- 0
- Pockets
- 37 · 3 records with a druggable one
Structures
18 records of P16455 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EH6 | Human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1EH6 | Human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1EH7 | Methylated human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1EH7 | Methylated human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1EH8 | Benzylated human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1EH8 | Benzylated human O6-alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1QNT | X-ray structure of human O6alkylguanine-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1QNT | X-ray structure of human O6ALKYLGUANINE-DNA alkyltransferase | x-ray diffraction | A | — | — |
| 1T38 | Human O6-alkylguanine-DNA alkyltransferase bound to DNA containing O6-methylguanine | x-ray diffraction | A | — | — |
| 1T38 | Human O6-alkylguanine-DNA alkyltransferase bound to DNA containing O6- methylguanine | x-ray diffraction | A | — | — |
| 1T39 | Human O6-alkylguanine-DNA alkyltransferase covalently crosslinked to DNA | x-ray diffraction | A, B | — | — |
| 1T39 | Human O6-alkylguanine-DNA alkyltransferase covalently crosslinked to DNA | x-ray diffraction | A, B | — | — |
| 1YFH | wt Human O6-Alkylguanine-DNA Alkyltransferase Bound To DNA Containing an Alkylated Cytosine | x-ray diffraction | A, B, C | — | — |
| 1YFH | Wt human O6-alkylguanine-DNA alkyltransferase bound to DNA containing an alkylated cytosine | x-ray diffraction | A, B, C | — | — |
| 8RGG | Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain… | electron microscopy | B | — | 13 (best 0.78) |
| 8RGH | Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain… | electron microscopy | A | — | 15 (best 0.84) |
| 8RTY | Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of… | electron microscopy | E, F | — | 9 (best 0.82) |
| P16455 | AlphaFold monomer V2.0 prediction for methylated-DNA--protein- cysteine methyltransferase (P16455) | — | — | — |
Experiment against prediction
- 8RTY chain E against the predicted model Q10059: TM-score 0.82, RMSD 1.65 Å
- 8RTY chain F against the predicted model Q10059: TM-score 0.81, RMSD 2.04 Å
Elsewhere
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