UniProt P15927
Replication protein A 32 kDa subunit (P15927)
Replication protein A 32 kDa subunit (UniProt P15927): 21 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15927
- Protein
- Replication protein A 32 kDa subunit
- Experimental structures
- 21
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
22 records of P15927 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DPU | Solution structure of the C-terminal domain of human RPA32 complexed with UNG2(73-88) | solution nmr | A | — | — |
| 1DPU | Solution structure of the C-terminal domain of human RPA32 complexed with UNG2(73-88) | solution nmr | A | — | — |
| 1L1O | Structure of the human Replication Protein A (RPA) trimerization core | x-ray diffraction | B, E | — | — |
| 1L1O | Structure of the human replication protein a (rpa) trimerization core | x-ray diffraction | B, E | — | — |
| 1QUQ | Complex of replication protein a subunits RPA14 and RPA32 | x-ray diffraction | A, C | — | — |
| 1QUQ | Complex of replication protein a subunits RPA14 and RPA32 | x-ray diffraction | A, C | — | — |
| 1Z1D | Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin… | solution nmr | A | — | — |
| 1Z1D | Structural model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin… | solution nmr | A | — | — |
| 2PI2 | Full-length Replication protein A subunits RPA14 and RPA32 | x-ray diffraction | A, B, C, D | — | — |
| 2PI2 | Full-length replication protein a subunits RPA14 and RPA32 | x-ray diffraction | A, B, C, D | — | — |
| 2PQA | Crystal Structure of Full-length Human RPA 14/32 Heterodimer | x-ray diffraction | A, C | — | — |
| 2PQA | Crystal structure of full-length human rpa 14/32 heterodimer | x-ray diffraction | A, C | — | — |
| 2Z6K | Crystal structure of full-length human RPA14/32 heterodimer | x-ray diffraction | A, B | — | — |
| 2Z6K | Crystal structure of full-length human RPA14/32 heterodimer | x-ray diffraction | A, B | — | — |
| 3KDF | X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free… | x-ray diffraction | D, B | — | — |
| 3KDF | X-ray crystal structure of the human replication protein a complex from wheat germ cell free… | x-ray diffraction | D, B | — | — |
| 4MQV | Crystal complex of Rpa32c and Smarcal1 N-terminus | x-ray diffraction | A, C | — | — |
| 4MQV | Crystal complex of RPA32C and SMARCAL1 N-terminus | x-ray diffraction | A, C | — | — |
| 4OU0 | Crystal Structure of RPA32C | x-ray diffraction | A | — | — |
| 4OU0 | Crystal structure of RPA32C | x-ray diffraction | A | — | — |
| 8RK2 | Human Replication protein A (RPA; trimeric core) - ssDNA complex | electron microscopy | B | — | 3 (best 0.81) |
| P15927 | AlphaFold monomer V2.0 prediction for replication protein a 32 kda subunit (P15927) | predicted | A | — | 2 (best 0.47) |
Experiment against prediction
- 3KDF chain D against the predicted model P15927: TM-score 0.98, RMSD 0.55 Å
- 3KDF chain D against the predicted model P15927: TM-score 0.98, RMSD 0.55 Å
- 2PI2 chain D against the predicted model P15927: TM-score 0.98, RMSD 0.67 Å
- 2PI2 chain D against the predicted model P15927: TM-score 0.98, RMSD 0.67 Å
- 3KDF chain B against the predicted model P15927: TM-score 0.98, RMSD 0.58 Å
- 3KDF chain B against the predicted model P15927: TM-score 0.98, RMSD 0.58 Å
- 8RK2 chain B against the predicted model P15927: TM-score 0.98, RMSD 0.63 Å
- 1L1O chain B against the predicted model P15927: TM-score 0.97, RMSD 0.77 Å
- 1L1O chain B against the predicted model P15927: TM-score 0.97, RMSD 0.77 Å
- 1QUQ chain A against the predicted model P15927: TM-score 0.97, RMSD 0.84 Å
Elsewhere
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