UniProt P15431
Gamma-aminobutyric acid receptor subunit beta-1,Gamma-aminobutyric acid receptor subunit beta-1 (P15431)
Gamma-aminobutyric acid receptor subunit beta-1,Gamma-aminobutyric acid receptor subunit beta-1 (UniProt P15431): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 10 pockets. Binding sites…
- UniProt
- P15431
- Protein
- Gamma-aminobutyric acid receptor subunit beta-1,Gamma-aminobutyric acid…
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 10 · 1 record with a druggable one
Structures
5 records of P15431 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DW0 | Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor… | electron microscopy | E, B | NAG, BMA, ABU | — |
| 6DW0 | Cryo-EM structure of the benzodiazepine-sensitive ALPHA1BETA1GAMMA2S tri-heteromeric gabaa receptor… | electron microscopy | E, B | NAG, BMA, ABU | — |
| 6DW1 | Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor… | electron microscopy | E, B | NAG, BMA, MAN, ABU | 10 (best 0.69) |
| 6DW1 | Cryo-EM structure of the benzodiazepine-sensitive ALPHA1BETA1GAMMA2S tri-heteromeric gabaa receptor… | electron microscopy | E, B | NAG, MAN, BMA, ABU | — |
| P15431 | AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit beta-1 (P15431) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6DW1 chain E against the predicted model P15431: TM-score 0.99, RMSD 0.48 Å
- 6DW1 chain E against the predicted model P15431: TM-score 0.99, RMSD 0.48 Å
- 6DW1 chain B against the predicted model P15431: TM-score 0.99, RMSD 0.52 Å
- 6DW1 chain B against the predicted model P15431: TM-score 0.99, RMSD 0.52 Å
- 6DW0 chain B against the predicted model P15431: TM-score 0.98, RMSD 0.94 Å
- 6DW0 chain B against the predicted model P15431: TM-score 0.98, RMSD 0.94 Å
- 6DW0 chain E against the predicted model P15431: TM-score 0.96, RMSD 1.23 Å
- 6DW0 chain E against the predicted model P15431: TM-score 0.96, RMSD 1.23 Å
Elsewhere
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