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UniProt P15428

15-hydroxyprostaglandin dehydrogenase [NAD(+)] (P15428)

15-hydroxyprostaglandin dehydrogenase [NAD(+)] (UniProt P15428), EC 1.1.1.-, 1.1.1.141: 4 experimental structures on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P15428
Protein
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
EC
1.1.1.-, 1.1.1.141, 1.1.1.232
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
7 · 1 record with a druggable one

Structures

4 records of P15428 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2GDZCrystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+x-ray diffractionA——
2GDZCrystal structure of 15-hydroxyprostaglandin dehydrogenase TYPE1, complexed with NAD+x-ray diffractionA——
8CVNCryo-EM Structure of Human 15-PGDH in Complex with Small Molecule SW209415electron microscopyA, BNAI, SWL7 (best 0.78)
P15428AlphaFold monomer V2.0 prediction for 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (P15428)———

Ligands

  • NAI · 1,4-dihydronicotinamide adenine dinucleotide · in 1 record
  • SWL · 2-[butyl(oxidanyl)-$l^{3}-sulfanyl]-4-(2,3-dimethylimidazol-4-yl)-6-(1,3-thiazol-2-yl)thieno[2,3-b]pyridin-3-amine · in 1 record

Elsewhere

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