UniProt P15391

B-lymphocyte antigen CD19 (P15391)

B-lymphocyte antigen CD19 (UniProt P15391): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P15391
Protein: B-lymphocyte antigen CD19
Experimental structures: 6
Predicted models: 1
Ligands: 1
Pockets: 9 · 2 records with a druggable one

Structures

7 records of P15391 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6AL5	Complex between CD19 (N138Q mutant) and B43 Fab	x-ray diffraction	A	NAG	—
6AL5	Complex between CD19 (N138Q mutant) and B43 Fab	x-ray diffraction	A	NAG	—
7JIC	Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment	electron microscopy	A	—	5 (best 0.71)
7JIC	Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment	electron microscopy	A	—	—
7URV	FMC63 scFv in complex with soluble CD19	electron microscopy	C	—	3 (best 0.54)
7URX	SJ25C1 Fab in complex with soluble CD19	electron microscopy	C	—	1 (best 0.49)
P15391	AlphaFold monomer V2.0 prediction for B-lymphocyte antigen CD19 (P15391)	predicted	A	—	—

Ligands

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records

Experiment against prediction

7URX chain C against the predicted model P15391: TM-score 0.98, RMSD 0.83 Å
7URV chain C against the predicted model P15391: TM-score 0.97, RMSD 0.95 Å
6AL5 chain A against the predicted model P15391: TM-score 0.96, RMSD 1.24 Å
6AL5 chain A against the predicted model P15391: TM-score 0.96, RMSD 1.24 Å
7JIC chain A against the predicted model P15391: TM-score 0.95, RMSD 1.48 Å
7JIC chain A against the predicted model P15391: TM-score 0.95, RMSD 1.48 Å

Elsewhere

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