UniProt P15260
Interferon gamma receptor 1 (P15260)
Interferon gamma receptor 1 (UniProt P15260): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15260
- Protein
- Interferon gamma receptor 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 3 records with a druggable one
Structures
11 records of P15260 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FG9 | 3:1 complex of interferon-gamma receptor with interferon-gamma dimer | x-ray diffraction | C, D, E | — | — |
| 1FG9 | 3:1 complex of interferon-gamma receptor with interferon- gamma dimer | x-ray diffraction | C, D, E | — | — |
| 1FYH | 1:1 complex between an interferon gamma single-chain variant and its receptor | x-ray diffraction | B, E | — | — |
| 1FYH | 1:1 complex between an interferon gamma single-chain variant and its receptor | x-ray diffraction | B, E | — | — |
| 1JRH | Complex (ANTIBODY/ANTIGEN) | x-ray diffraction | I | — | — |
| 1JRH | Complex (ANTIBODY/ANTIGEN) | x-ray diffraction | I | — | — |
| 6E3K | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | C, D | NAG | 6 (best 0.78) |
| 6E3K | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | C, D | NAG | — |
| 6E3L | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | C, D | NAG | 8 (best 0.76) |
| 6E3L | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | x-ray diffraction | C, D | NAG | — |
| P15260 | AlphaFold monomer V2.0 prediction for interferon gamma receptor 1 (P15260) | predicted | A | — | 1 (best 0.54) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 6E3L chain C against the predicted model P15260: TM-score 0.98, RMSD 0.80 Å
- 6E3L chain C against the predicted model P15260: TM-score 0.98, RMSD 0.80 Å
- 6E3K chain D against the predicted model P15260: TM-score 0.98, RMSD 0.82 Å
- 6E3K chain D against the predicted model P15260: TM-score 0.98, RMSD 0.82 Å
- 6E3L chain D against the predicted model P15260: TM-score 0.98, RMSD 0.83 Å
- 6E3L chain D against the predicted model P15260: TM-score 0.98, RMSD 0.83 Å
- 6E3K chain C against the predicted model P15260: TM-score 0.98, RMSD 0.89 Å
- 6E3K chain C against the predicted model P15260: TM-score 0.98, RMSD 0.89 Å
- 1FYH chain E against the predicted model P15260: TM-score 0.97, RMSD 1.00 Å
- 1FYH chain E against the predicted model P15260: TM-score 0.97, RMSD 1.00 Å
Elsewhere
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