UniProt P15104
Glutamine synthetase (P15104)
Glutamine synthetase (UniProt P15104), EC 2.3.1.225, 6.3.1.2: 7 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 114 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P15104
- Protein
- Glutamine synthetase
- EC
- 2.3.1.225, 6.3.1.2
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 114 · 6 records with a druggable one
Structures
8 records of P15104 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OJW | Crystal structure of human glutamine synthetase in complex with ADP and phosphate | x-ray diffraction | A, B, C, D, E | MN, PO4, CL, ADP | 17 (best 0.80) |
| 2OJW | Crystal structure of human glutamine synthetase in complex with ADP and phosphate | x-ray diffraction | A, B, C, D, E | MN, PO4, CL, ADP | 17 (best 0.80) |
| 2QC8 | Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | MN, CL, ADP, P3S | 20 (best 0.76) |
| 2QC8 | Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | MN, CL, ADP, P3S | 20 (best 0.76) |
| 7EVT | Crystal structure of the N-terminal degron-truncated human glutamine synthetase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | 20 (best 0.77) |
| 7EVT | Crystal structure of the N-terminal degron-truncated human glutamine synthetase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | — | — |
| 8DNU | Human Brain Glutamine Synthetase | electron microscopy | A, B, C, D, E, F, G, H, I, J | MN | 20 (best 0.79) |
| P15104 | AlphaFold monomer V2.0 prediction for glutamine synthetase (P15104) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7EVT chain C against the predicted model P15104: TM-score 1.00, RMSD 0.37 Å
- 7EVT chain C against the predicted model P15104: TM-score 1.00, RMSD 0.37 Å
- 8DNU chain H against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain J against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain A against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain B against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain F against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain I against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain G against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
- 8DNU chain C against the predicted model P15104: TM-score 1.00, RMSD 0.39 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.