UniProt P14921
P14921
P14921 (UniProt P14921): 41 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14921
- Experimental structures
- 41
- Predicted models
- 1
Structures
42 records of P14921 in the MolNFT archive: 41 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GVJ | Ets-1 DNA binding and autoinhibitory domains | x-ray diffraction | A, B | — | — |
| 1GVJ | Ets-1 DNA binding and autoinhibitory domains | x-ray diffraction | A, B | — | — |
| 2NNY | Crystal structure of the Ets1 dimer DNA complex. | x-ray diffraction | A, B | — | — |
| 2NNY | Crystal structure of the ETS1 dimer DNA complex. | x-ray diffraction | A, B | — | — |
| 2STT | Solution NMR structure of the human ETS1/DNA complex, 25 structures | solution nmr | A | — | — |
| 2STT | Solution NMR structure of the human ETS1/DNA complex, 25 structures | solution nmr | A | — | — |
| 2STW | Solution NMR structure of the human ETS1/DNA complex, restrained regularized mean structure | solution nmr | A | — | — |
| 2STW | Solution NMR structure of the human ETS1/DNA complex, restrained regularized mean structure | solution nmr | A | — | — |
| 3MFK | Ets1 complex with stromelysin-1 promoter DNA | x-ray diffraction | A, B | — | — |
| 3MFK | ETS1 complex with stromelysin-1 promoter DNA | x-ray diffraction | A, B | — | — |
| 3RI4 | Ets1 cooperative binding to widely separated sites on promoter DNA | x-ray diffraction | A, D | — | — |
| 3RI4 | ETS1 cooperative binding to widely separated sites on promoter DNA | x-ray diffraction | A, D | — | — |
| 3WTS | Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer… | x-ray diffraction | C, H | — | — |
| 3WTS | Crystal structure of the complex comprised of ETS1, RUNX1, cbfbeta, and the tcralpha gene enhancer… | x-ray diffraction | C, H | — | — |
| 3WTT | Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha… | x-ray diffraction | C, H | — | — |
| 3WTT | Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, cbfbeta, and the tcralpha… | x-ray diffraction | C, H | — | — |
| 3WTU | Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTU | Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTV | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTV | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTW | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTW | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTX | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTX | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTY | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTY | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | C, H | — | — |
| 3WTZ | Crystal structure of ETS-1 DNA binding and autoinhibitory domains (276-441) | x-ray diffraction | A, B | — | — |
| 3WTZ | Crystal structure of ets-1 DNA binding and autoinhibitory domains (276-441) | x-ray diffraction | A, B | — | — |
| 3WU0 | Crystal structure of phosphorylated ETS-1 DNA binding and autoinhibitory domains (276-441) | x-ray diffraction | A, B | — | — |
| 3WU0 | Crystal structure of phosphorylated ets-1 DNA binding and autoinhibitory domains (276-441) | x-ray diffraction | A, B | — | — |
| 3WU1 | Crystal structure of the ETS1-RUNX1-DNA ternary complex | x-ray diffraction | B | — | — |
| 3WU1 | Crystal structure of the ETS1-RUNX1-DNA ternary complex | x-ray diffraction | B | — | — |
| 4L0Y | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1) | x-ray diffraction | B | — | — |
| 4L0Y | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 1) | x-ray diffraction | B | — | — |
| 4L0Z | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2) | x-ray diffraction | B | — | — |
| 4L0Z | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 2) | x-ray diffraction | B | — | — |
| 4L18 | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3) | x-ray diffraction | B, F | — | — |
| 4L18 | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 3) | x-ray diffraction | B, F | — | — |
| 4LG0 | Structure of a ternary FOXO1-ETS1 DNA complex | x-ray diffraction | B | — | — |
| 4LG0 | Structure of a ternary FOXO1-ETS1 DNA complex | x-ray diffraction | B | — | — |
| 5ZMC | Structural basis for reactivation of -146C>T mutant tert promoter by cooperative binding of P52 and… | x-ray diffraction | B | — | — |
| P14921 | AlphaFold monomer V2.0 prediction for protein C-ets-1 (P14921) | predicted | A | — | — |
Experiment against prediction
- 4L0Y chain B against the predicted model P14921: TM-score 0.98, RMSD 0.50 Å
- 4L0Y chain B against the predicted model P14921: TM-score 0.98, RMSD 0.50 Å
- 3WTX chain C against the predicted model P14921: TM-score 0.98, RMSD 0.54 Å
- 3WTX chain C against the predicted model P14921: TM-score 0.98, RMSD 0.54 Å
- 4L18 chain B against the predicted model P14921: TM-score 0.98, RMSD 0.79 Å
- 4L18 chain B against the predicted model P14921: TM-score 0.98, RMSD 0.79 Å
- 4LG0 chain B against the predicted model P14921: TM-score 0.98, RMSD 0.60 Å
- 4LG0 chain B against the predicted model P14921: TM-score 0.98, RMSD 0.60 Å
- 3WU1 chain B against the predicted model P14921: TM-score 0.97, RMSD 0.84 Å
- 3WU1 chain B against the predicted model P14921: TM-score 0.97, RMSD 0.84 Å
Elsewhere
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