UniProt P14904
Vacuolar aminopeptidase 1 (P14904)
Vacuolar aminopeptidase 1 (UniProt P14904), EC 3.4.11.22: 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 55 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14904
- Protein
- Vacuolar aminopeptidase 1
- EC
- 3.4.11.22
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 55 · 3 records with a druggable one
Structures
11 records of P14904 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4R8F | Crystal structure of yeast aminopeptidase 1 (Ape1) | x-ray diffraction | A, B, C, D | — | — |
| 4R8F | Crystal structure of yeast aminopeptidase 1 (APE1) | x-ray diffraction | A, B, C, D | — | — |
| 5JGF | Crystal structure of mApe1 | x-ray diffraction | A, B, C, D | ZN | 20 (best 0.83) |
| 5JGF | Crystal structure of MAPE1 | x-ray diffraction | A, B, C, D | — | — |
| 5JH9 | Crystal structure of prApe1 | x-ray diffraction | A, B, C, D | ZN | 20 (best 0.84) |
| 5JH9 | Crystal structure of PRAPE1 | x-ray diffraction | A, B, C, D | — | — |
| 5JHC | Crystal structure of the self-assembled propeptides from Ape1 | x-ray diffraction | A, C, E, G, I, K, M, O, Q, S, U, W, Y, B, a, b, D, F, c, H, d, J, e, L, f, N, g, P, h, R, i, T, j, V, k, X, l, Z, m | — | 15 (best 0.83) |
| 5JHC | Crystal structure of the self-assembled propeptides from APE1 | x-ray diffraction | A, C, E, G, I, K, M, O, Q, S, U, W, Y, B, a, b, D, F, c, H, d, J, e, L, f, N, g, P, h, R, i, T, j, V, k, X, l, Z, m | — | — |
| 5JM9 | Structure of S. cerevesiae mApe1 dodecamer | electron microscopy | A | — | — |
| 5JM9 | Structure of S. cerevesiae MAPE1 dodecamer | electron microscopy | A | — | — |
| P14904 | AlphaFold monomer V2.0 prediction for vacuolar aminopeptidase 1 (P14904) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 5JGF chain B against the predicted model P14904: TM-score 1.00, RMSD 0.27 Å
- 5JGF chain B against the predicted model P14904: TM-score 1.00, RMSD 0.27 Å
- 5JGF chain A against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 5JGF chain A against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 5JGF chain C against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 5JGF chain C against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 5JGF chain D against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 5JGF chain D against the predicted model P14904: TM-score 1.00, RMSD 0.28 Å
- 4R8F chain C against the predicted model P14904: TM-score 0.99, RMSD 0.83 Å
- 4R8F chain C against the predicted model P14904: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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